Executive functions and autism traits in SCT compared to typically developing children

Individuals with a SCT characterized with an additional X chromosome encounter difficulties in social functioning, which is most prominent in there higher susceptibility for developing autism. The current study aimed to systematically address underlying mechanisms related to these difficulties by examining differences in executive functions of children with a SCT karyotype and typically developing children. Furthermore, we examined to what extent executive function deficits were related to higher autism traits. 135 boys and girls (M = 11.4, SD = .2) participated in this study, 85 typically developing children and 50 children with a SCT. We used computerized tasks, a questionnaire, and a verbal task to asses a wide range of executive functions. A questionnaire was used to address autism traits. Children with a SCT showed increased difficulties in encoding verbal information, cognitive flexibility, sustained attention, and more difficulties in executive functions during daily life...Show moreIndividuals with a SCT characterized with an additional X chromosome encounter difficulties in social functioning, which is most prominent in there higher susceptibility for developing autism. The current study aimed to systematically address underlying mechanisms related to these difficulties by examining differences in executive functions of children with a SCT karyotype and typically developing children. Furthermore, we examined to what extent executive function deficits were related to higher autism traits. 135 boys and girls (M = 11.4, SD = .2) participated in this study, 85 typically developing children and 50 children with a SCT. We used computerized tasks, a questionnaire, and a verbal task to asses a wide range of executive functions. A questionnaire was used to address autism traits. Children with a SCT showed increased difficulties in encoding verbal information, cognitive flexibility, sustained attention, and more difficulties in executive functions during daily life compared to the typically developing children. Higher autism traits were associated with more difficulties in executive functions during daily life, cognitive flexibility, and encoding verbal information. This provides evidence for impairments in executive functions among individuals with a SCT of which some of them are related to increased difficulties in social functioning. Limitations and implications for future research are discussed.Show less

Leiden University Student Repository

Documents

In Collections

Executive functions and autism traits in SCT compared to typically developing children