Bone Loss in Osteoarchaeology: An exploration of Quantitative Computed Tomography (QCT) and Dual-Energy X-ray Absorptiometry (DEXA) assessments of age-related bone loss in a 19th  Century Dutch Sample.

Age-related bone loss has been receiving a lot of attention in recent years in an attempt to assess and treat conditions that are affected by bone loss such as osteopenia. Current bone loss influences are reviewed as well as an overview of bone loss assessment in archaeological material. This research evaluated age-related bone loss in a 19th Century Dutch osteoarchaeological population to determine frailty rates through Quantitaitive Computed Tomography (QCT) and Dual- Energy X-ray Absoorptiometry (DEXA) of loading (femur) and non-loading (humerus) elements. An examination of areal bone mineral density (aBMD) and volumatic (vBMD) were explored in correlation to trabecular architecture. It was determined bone loss was present within in the population however, the onset of osteoporotic fracture risk was unable to be determined. Male loading and non-loading bones exhibit consistent changes in trabecular connectivity and connectivity volume while females are more likely affected by an...Show moreAge-related bone loss has been receiving a lot of attention in recent years in an attempt to assess and treat conditions that are affected by bone loss such as osteopenia. Current bone loss influences are reviewed as well as an overview of bone loss assessment in archaeological material. This research evaluated age-related bone loss in a 19th Century Dutch osteoarchaeological population to determine frailty rates through Quantitaitive Computed Tomography (QCT) and Dual- Energy X-ray Absoorptiometry (DEXA) of loading (femur) and non-loading (humerus) elements. An examination of areal bone mineral density (aBMD) and volumatic (vBMD) were explored in correlation to trabecular architecture. It was determined bone loss was present within in the population however, the onset of osteoporotic fracture risk was unable to be determined. Male loading and non-loading bones exhibit consistent changes in trabecular connectivity and connectivity volume while females are more likely affected by an increase in trabecular bone volume. Humeral BMC data between DEXA and QCT indicated that a possible calibration curve can be determined suggesting that the humerus is a good indicator of age-related bone loss. Subsequently, the term “osteopenia” was determined to be invalid for this assessment and the term “bone loss” is thus suggested to be used.Show less

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Bone Loss in Osteoarchaeology: An exploration of Quantitative Computed Tomography (QCT) and Dual-Energy X-ray Absorptiometry (DEXA) assessments of age-related bone loss in a 19th Century Dutch Sample.