A Network Analysis of Obsessive-Compulsive Disorder and Its Common Comorbidities

Obsessive-compulsive disorder (OCD) commonly co-occurs with other psychiatric conditions. In recent years, network analysis has been employed to investigate the relationship between OCD and some of its comorbidities. The objective of the current thesis was to explore the comorbidity network of OCD in relation to seven other psychiatric conditions, some of whose interactions with OCD have not been investigated by the former network analysis papers. The thesis made use of an open-source data which was collected from patients who registered to the Behavioural Health Partial (BHP) hospital program at McLean Hospital, Massachusetts between 30 November 2018–16 October 2019. The final sample consisted of 532 people. Their responses to four measures, namely Obsessive-Compulsive and Related Disorders Dimensional Scales, Patient Health Questionnaire, Generalized Anxiety Disorder Scale, Drug Alcohol Craving Scale were analysed using network analysis. In total, we estimated two regularized...Show moreObsessive-compulsive disorder (OCD) commonly co-occurs with other psychiatric conditions. In recent years, network analysis has been employed to investigate the relationship between OCD and some of its comorbidities. The objective of the current thesis was to explore the comorbidity network of OCD in relation to seven other psychiatric conditions, some of whose interactions with OCD have not been investigated by the former network analysis papers. The thesis made use of an open-source data which was collected from patients who registered to the Behavioural Health Partial (BHP) hospital program at McLean Hospital, Massachusetts between 30 November 2018–16 October 2019. The final sample consisted of 532 people. Their responses to four measures, namely Obsessive-Compulsive and Related Disorders Dimensional Scales, Patient Health Questionnaire, Generalized Anxiety Disorder Scale, Drug Alcohol Craving Scale were analysed using network analysis. In total, we estimated two regularized partial correlation networks. The first network consisted of eight nodes representing eight psychiatric conditions. Differing from the former network in one way, the second one represented OCD and depression at a symptom level. Network 1 showed that OCD was connected to all other obsessive-compulsive and related disorder (OCRD)’s and generalized anxiety disorder (GAD) but not to depression and drug alcohol craving. In this network, OCD was only linked to depression through other OCRD’s and GAD. Further, our results highlighted the importance of fatigue as it was one of the most central nodes in Network 2.Show less

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A Network Analysis of Obsessive-Compulsive Disorder and Its Common Comorbidities