Leiden University Student Repository

Hendriksen, Jiska (2022)

Therapeutic Hypothermia effects on cognition in children with Perinatal Asphyxia: A possible interaction with birthweight and long-term effects exploration

Master thesis | Psychology (MSc)

Children who are born with perinatal asphyxia (PA) in the Netherlands, have been treated with therapeutic hypothermia (TH) since 2018. So far, little is known about the cognitive outcome of these children. This study explores a possible interaction effect between birthweight and TH on Total IQ and Processing Speed in children 10 years of age known with PA. Some of the children treated with TH were also cognitive assessed at the age of 5 year. For these children, we looked at the course of cognitive development between 5 and 10 years of age. Fifty children were assessed at the age of 10 years with the Wechsler intelligence scale (WISC-III-NL). Fifteen of these children were also assessed at the age of 5 years with the Wechsler Preschool and Primary Scale of intelligence (WPPSI-III-NL). There was no interaction effect found between TH and birthweight on Total IQ and processing speed scores assessed at the age of 10 years. Furthermore, there were no significant differences found...Show moreChildren who are born with perinatal asphyxia (PA) in the Netherlands, have been treated with therapeutic hypothermia (TH) since 2018. So far, little is known about the cognitive outcome of these children. This study explores a possible interaction effect between birthweight and TH on Total IQ and Processing Speed in children 10 years of age known with PA. Some of the children treated with TH were also cognitive assessed at the age of 5 year. For these children, we looked at the course of cognitive development between 5 and 10 years of age. Fifty children were assessed at the age of 10 years with the Wechsler intelligence scale (WISC-III-NL). Fifteen of these children were also assessed at the age of 5 years with the Wechsler Preschool and Primary Scale of intelligence (WPPSI-III-NL). There was no interaction effect found between TH and birthweight on Total IQ and processing speed scores assessed at the age of 10 years. Furthermore, there were no significant differences found between Total IQ and processing speed scores assessed at 5 and 10 years of age. Since this was only exploratory research more research is needed to draw more reliable conclusions.Show less

Therapeutic Hypothermia

cognition

children

birthweight

Perinatal Asphyxia

Author

Hendriksen, Jiska

Faculty

Faculty of Social & Behavioural Sciences

Specialisation

Clinical Neuropsychology

Supervisors

Houdt, C.A. van

ECTS Credits

20

Language

en