Leiden University Student Repository

Zalen, T.M.J. van (2011)

Modular Response Analysis: A method for reconstructing chemical networks

Bachelor thesis | Wiskunde (BSc)

This Bachelor thesis is about the Modular Response Analysis, a method to reconstruct a biochemal network from experimental data. It mathematically describes two methods, one based on the results from the steady state of a chemical network, and one based on the results of different time series in a chemical network. For these methods, also the Singular Value Decomposition is described. This decomposition is helpful in solving overdetermined systems of equations, which is a common situation when applying these methods in an experimental environment.

Author

Zalen, T.M.J. van

Faculty

Faculty of Science

Supervisors

Hille, S.C.

ECTS Credits

18

Language

en