The Effect of Virtual Reality Psychoeducation on Self-Stigma and Depressive Symptoms in Patients with Major Depressive Disorder

Background: Many patients with Major Depressive Disorder (MDD) suffer from self-stigma. Self-stigma can lead to a decrease in recovery speed and treatment adherence. Psychoeducation for depression has shown to be effective in improving treatment adherence and self-stigma. In recent years, researchers investigated Virtual reality (VR) as a potential tool in the treatment of depression. Studies have shown that VR interventions can reduce, among other things, self-stigma and depressive symptoms. We investigated the impact of a VR experience combined with psychoeducation compared to traditional, non-VR psychoeducation on self-stigma and depressive symptoms in individuals with MDD. We expected the VR intervention to have a more positive effect in reducing self-stigma and depressive symptoms than non-VR. Methods: The 31 recruited participants, aged 18-65 years old, were randomized into two groups: VR and non-VR. Two 360-degree VR videos were developed to experience a day in the life of a...Show moreBackground: Many patients with Major Depressive Disorder (MDD) suffer from self-stigma. Self-stigma can lead to a decrease in recovery speed and treatment adherence. Psychoeducation for depression has shown to be effective in improving treatment adherence and self-stigma. In recent years, researchers investigated Virtual reality (VR) as a potential tool in the treatment of depression. Studies have shown that VR interventions can reduce, among other things, self-stigma and depressive symptoms. We investigated the impact of a VR experience combined with psychoeducation compared to traditional, non-VR psychoeducation on self-stigma and depressive symptoms in individuals with MDD. We expected the VR intervention to have a more positive effect in reducing self-stigma and depressive symptoms than non-VR. Methods: The 31 recruited participants, aged 18-65 years old, were randomized into two groups: VR and non-VR. Two 360-degree VR videos were developed to experience a day in the life of a patient with depression. Self-stigma and depressive symptoms were measured before intervention (T0), directly after intervention (T1, only self-stigma), after 1 week (T2), and a follow-up after 10 weeks (T3). A repeated measures ANOVA was used for comparing the treatment groups. Results: Contrary to the hypothesis, the repeated measures ANOVA results indicated no significant interaction effect between time and treatment group for self-stigma (p = .393). In terms of depressive symptoms, a repeated measures ANOVA revealed a significant interaction effect between time and treatment group (p = .027), with a medium effect size (η2 = .095). Post hoc testing using Bonferroni showed that non-VR significantly decreased depressive symptoms across different time points compared to VR. Additionally, post hoc testing revealed that self-stigma and depressive symptoms may be positively correlated. Conclusion: No significant difference was found between the two treatment conditions in terms of decreasing self-stigma. However, the non-VR condition demonstrated a significant decrease in depressive symptoms compared to the VR condition. Additionally, positive correlations were observed between self-stigma and depressive symptoms, which emphasize the value of incorporating psychoeducation into treatment plans for people with MDD.Show less

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The Effect of Virtual Reality Psychoeducation on Self-Stigma and Depressive Symptoms in Patients with Major Depressive Disorder