Memory performance of Hashimoto’s Thyroiditis patients with residual symptoms after LT4 monotherapy

Hashimoto’s thyroiditis is a common autoimmune disorder. Hashimoto’s thyroiditis patients may experience cognitive impairments such as memory problems, even after receiving LT4-monotherapy. This study investigates the memory performance of Hashimoto’s thyroiditis patients with residual symptoms after receiving LT4 monotherapy, utilizing participants from the T3-4 Hypo Trial. Memory performance was assessed using the Rey Auditory Verbal Learning Test (RAVLT) 15-Word Task and the data were compared to normative data from the Advanced Neuropsychological Diagnostics Infrastructure Norms (ANDI-Norms). Results indicate that Hashimoto’s thyroiditis patients do not significantly perform different to the general population. This study investigated whether age and sex are potential predictors of memory performance. These factors showed no significant results suggesting that they are not related to memory performance. However, this study does highlight limitations such as possible comorbidity,...Show moreHashimoto’s thyroiditis is a common autoimmune disorder. Hashimoto’s thyroiditis patients may experience cognitive impairments such as memory problems, even after receiving LT4-monotherapy. This study investigates the memory performance of Hashimoto’s thyroiditis patients with residual symptoms after receiving LT4 monotherapy, utilizing participants from the T3-4 Hypo Trial. Memory performance was assessed using the Rey Auditory Verbal Learning Test (RAVLT) 15-Word Task and the data were compared to normative data from the Advanced Neuropsychological Diagnostics Infrastructure Norms (ANDI-Norms). Results indicate that Hashimoto’s thyroiditis patients do not significantly perform different to the general population. This study investigated whether age and sex are potential predictors of memory performance. These factors showed no significant results suggesting that they are not related to memory performance. However, this study does highlight limitations such as possible comorbidity, uneven distribution of sex and education levels that need consideration. Future research is advised to better understand the complex relationship between Hashimoto’s thyroiditis and cognitive function. This study contributes to the broader understanding of the relationship between cognitive function and Hashimoto’s thyroiditis and underscores the need for future research to develop effective and/or improve existing clinical management strategies.Show less

Leiden University Student Repository

Documents

In Collections

Memory performance of Hashimoto’s Thyroiditis patients with residual symptoms after LT4 monotherapy