Leiden University Student Repository

Overdevest, Remco (2018)

Sensitivity of Electrical Properties Tomography

Master thesis | Physics (MSc)

In this thesis we investigate conductivity changes due to magnetite in agarose gels mimicking grey brain matter. We use conventional MRI sequences to acquire B + 1 phase maps. Using the homogeneous Helmholtz equation and the B + 1 phase-only approximation, we reconstruct conductivity maps. The current sensitivity of the reconstructions is too low to detect conductivity changes due to magnetite nanoparticles in the concentration found in the brain of Alzheimer’s disease patients. Nevertheless, we have promising indications that we have been able to observe a change in the standard deviation of the conductivity due to the presence of magnetite.

Tomography

MRI

Conductivity

Reconstruction

Author

Overdevest, Remco

Faculty

Faculty of Science

Specialisation

Physics, Quantum Matter and Optics

Supervisors

Bossoni, Lucia

ECTS Credits

3

Evaluation

Recommended

Language

en