Parkinson’s disease (PD) is a neurodegenerative disorder characterized primarily by motor symptoms due to the degeneration of dopaminergic neurons. However, non-motor symptoms such as cognitive...Show moreParkinson’s disease (PD) is a neurodegenerative disorder characterized primarily by motor symptoms due to the degeneration of dopaminergic neurons. However, non-motor symptoms such as cognitive decline are prevelant in up to 80% of PD patients. Multi-system degeneration and neurotransmitter decifiences are likely the cause. One of the systems implicated in PD-related cognitive decline is the cholinergic system but it remains unclear to what extent the system is affected and how it links to different disease stages. This retrospective cohort study explores the integrity of the cholinergic system in PD through the measurement of alpha reactivity using electroencephalography (EEG). EEG data from 191 participants, including 46 early-stage PD patients, 17 late-stage PD patients, and 128 healthy controls was analyzed. Alpha reactivity, measured as the difference in alpha power between eyes closed and eyes open conditions, was assessed via EEG. Cognition was assessed via the Mini-Mental State Exam (MMSE). Results revealed significantly reduced alpha reactivity in PD patients compared to healthy controls. ANCOVA analyses demonstrated reductions in alpha reactivity in both early-stage and late-stage PD groups when compared to healthy controls. However, no significant reduction in alpha reactivity was found between early and late-stage PD patients. These findings provide neurophysiological evidence of a reduction in alpha reactivity in PD patients, which could indicate a cholinergic dysfunction in PD, irrespective of disease stage. This study also highlights the potential utility of alpha reactivity as a biomarker for assessing disease severity.Show less
Education serves as a pivotal driver of societal advancement, yet persistent obstacles hinder universal access to quality education in low-middle-income countries. Concurrently, the phenomenon of...Show moreEducation serves as a pivotal driver of societal advancement, yet persistent obstacles hinder universal access to quality education in low-middle-income countries. Concurrently, the phenomenon of brain drain, characterized by the migration of skilled individuals to foreign shores, poses a considerable challenge to these nations. This study employs linear regression analysis to delve into the impact of educational assistance on emigration rates, with a particular focus on the dynamics of brain drain. Drawing from diverse theoretical frameworks, including Schumpeter's theory and insights gleaned from entrepreneurship studies, this research formulates hypotheses to elucidate the relationship between educational development and emigration. It undertakes a comprehensive examination of perspectives surrounding brain drain and delineates the role of education in nurturing sustainable development, with the overarching goal of unraveling the intricate interplay between education and emigration. This research contributes to the discourse on development by offering evidence-based insights into the complications of education assistance affecting brain drain. By understanding the nexus between education and emigration, policymakers can formulate targeted strategies to harness youth talent and drive economic progress in low-middle-income countries, without driving them abroad.Show less
This thesis explores the concept of linguistic secession and its implications within the framework of international law, focusing on the case studies of Québec and Abkhazia. Through a detailed...Show moreThis thesis explores the concept of linguistic secession and its implications within the framework of international law, focusing on the case studies of Québec and Abkhazia. Through a detailed examination of historical contexts, it highlights how linguistic identity can fuel secessionist movements and evaluates the extent to which linguistic discrimination can justify claims for independence. By analysing legal doctrines and international treaties, the study assesses the applicability of remedial secession as a response to linguistic subjugation. The findings suggest that while language plays a pivotal role in shaping national identity, the legitimacy of secession based on linguistic grounds remains contentious. The research underscores the importance of ensuring that internal self-determination is properly implemented and the need of protecting linguistic rights within existing state structures, offering insights into the evolving nature of self-determination in the global legal landscape.Show less
The actual numbers of international climate-related migration are not as large as expected, considering the rapid increase in the uninhabitability of these places in the Global South. This...Show moreThe actual numbers of international climate-related migration are not as large as expected, considering the rapid increase in the uninhabitability of these places in the Global South. This discrepancy may partly stem from the complex and multifaceted nature of migration, with the climate factors influencing economic opportunity and conflict, making it difficult to differentiate between people that migrate for climate reasons and people that migrate for other reasons, such as economic opportunities. However, it more likely arises from people being trapped within their increasingly uninhabitable homes, because they do not have the capacity to move or willingness to leave their home. Therefore, policymakers and researchers should redirect their attention to immobility, as the ‘trapped populations’ are an urgent and underexposed problem. This thesis will examine the term 'trapped populations,' by using conceptions of Zickgraf (2019, 2023) and De Shalit (2011) and clarifying the complexities inherent in their immobility. I will argue for ‘the right to stay’ as the most protective right for the interests of the trapped populations, as it respects the importance of a home in a person their life.Show less
Since 2014, Europe has faced an explosive increase in migrants, leading Europe into a migration crisis. Political parties in European countries have responded differently to this influx of people....Show moreSince 2014, Europe has faced an explosive increase in migrants, leading Europe into a migration crisis. Political parties in European countries have responded differently to this influx of people. This study aims to clarify the relationship between the agenda of these political parties and the European migration crisis. Based on qualitative research, a content analysis was used to study the differences between left-wing, right-wing and centre-parties and how the European migration crisis has impacted these points of view. The analysis shows that political parties with different ideologies about migration react differently to the crisis. The European migration crisis has little to no effect on the agenda of left-wing parties and right-wing parties, but a major effect on the agendas of centre-parties.Show less
This thesis looks into the effects of horizontal inequalities on civilian victimisation during civil wars. The contribution of this paper is two-fold. First, it gave an extensive overview of...Show moreThis thesis looks into the effects of horizontal inequalities on civilian victimisation during civil wars. The contribution of this paper is two-fold. First, it gave an extensive overview of relevant research from numerous fields, which were subsequently combined into one overarching theoretical framework. Secondly, a preliminary empirical analysis was conducted using multiple linear regression (OLS) models to test the resulting expectations - that horizontal inequalities (economic and political) are likely positively related to civilian victimisation during civil wars. The analysis came back with mixed results, and at best limited and indirect support for the expected positive link between horizontal inequality and civilian victimisation.Show less
This thesis examines the dynamics of the military-industrial complex and its impact on defense procurement and foreign relations within the European Union. Analyzing the Dutch submarine order and...Show moreThis thesis examines the dynamics of the military-industrial complex and its impact on defense procurement and foreign relations within the European Union. Analyzing the Dutch submarine order and Rheinmetall's industrial expansion into Ukraine, it explores the interplay between government policies, corporate interests, and international security. Utilizing realism and corporatism, the study highlights how states and industries navigate defense procurement to achieve national security and economic goals. Realism emphasizes state interests and competition, which is utilized by the military-industrial complex to their advantage. Corporatism focuses on collaborative interactions between government and industry which can be used by governments to get the best offer. The findings reveal that defense procurement is influenced by government priorities, key players, corporate strategies, and lobbying. Overall, this research provides insights into the military-industrial complex's role in shaping EU defense policies and international relations.Show less
Environmental protection is an increasingly salient topic for contemporary society, especially in the context of the climate crisis. People all around the world are engaging in environmental...Show moreEnvironmental protection is an increasingly salient topic for contemporary society, especially in the context of the climate crisis. People all around the world are engaging in environmental activism, yet environmentalism research has disproportionately centered on the West. Considering how most countries on the front lines of climate change are non-Western, this gap must be rectified. Southeast Asia (SEA) is a region severely overlooked in this regard, particularly in terms of what environmentalism actually brings here. There is insufficient knowledge on how SEA states respond to environmental activism, despite the relevance for its citizens and environmental sector practitioners, who witness some of the worst repercussions of environmental degradation. Therefore, this paper aims to expand our understanding of state responses to SEA environmentalism and contentious political action by investigating Vietnam and the Philippines. A comparative study was conducted on these two cases, which employed qualitative content analysis on texts like news articles to study responses to environmentalism. Findings reveal that both countries display a variety of responses, but are most inclined to repress. However, they differ considerably in how they approach each response type in terms of methods, actors involved, and consistency. It is proposed that each country’s distinct response pattern is linked to its respective regime type, as suggested by existing literature on contentious political action. Beyond the popular notion that non-democracies are more likely to repress contentious claim-making, this study illustrates how hybrid regimes can be more covert and lethal in their repression than other regimes. From these findings, this paper stresses the importance of local socio-political contexts for those engaged in environmental protection and advocacy. Additionally, this investigation hopes to spur similar research on other SEA countries and expand the political science literature on this region.Show less
The ‘Women, Life, Freedom’ Movement that started in 2022 in Iran brought another wave of women’s rights movement. The involvement of Iranian diaspora communities in cyberspace successfully...Show moreThe ‘Women, Life, Freedom’ Movement that started in 2022 in Iran brought another wave of women’s rights movement. The involvement of Iranian diaspora communities in cyberspace successfully transformed this movement into the online sphere. This paper seeks to answer the following research questions: How do Iranian diaspora communities construct identity through cyberfeminism in the 'Women, Life, Freedom' movement? The paper aims to explore the effectiveness of cyberfeminism and more importantly, it aims to identity the role of X and diasporic websites in constructing Iranian diaspora’s identity through an inductive approach. Frame theory is utilized as a lens to examine how Iranian diasporas frame themselves in the cyberspace and make connections between those inside and outside Iran. This paper finds three framing strategies, namely: identification of common enemies, victimization, and empowerment of women that contribute to forming a collective identity within diasporas.Show less
There is a strong upward trend in the amounts spent on development aid. In 2022, the total amount of Overseas Development Assistance (ODA) was five times higher than in 1960. The European Union is...Show moreThere is a strong upward trend in the amounts spent on development aid. In 2022, the total amount of Overseas Development Assistance (ODA) was five times higher than in 1960. The European Union is responsible for about two-thirds of humanitarian aid worldwide. However, it is questionable whether development aid is actually effective. A ‘least-likely case’ is Nigeria, it received 9 billion euros from the EU in the period of 2007-2024. Yet it has one of the worst development factors in Sub-Saharan Africa. This Thesis aims to find an answer to the question of whether European development aid was really effective in Nigeria, and whether the targets the European Union set itself were actually achieved. This is done by using the National Indicative Programme (NIP) that ran from 2014-2020. The analysis shows that despite achieving some of the objectives examined in the health care sector, the NIP has mostly failed to achieve the desired impact. Primarily, the high level of corruption ensured that few development objectives have been realized. Therefore, it can be concluded that European Development aid has not really been effective. For further research, it would be valuable to look at the Multi-Annual Indicative Programme (MIP) that runs from 2021-2027. Here, slightly different targets have been set that may give different results. In addition, it may be of added value to conduct a study of how Nigerian agencies report, since there are sometimes substantial differences between the observations of NGOs and these agencies, which can lead to different interpretations. This could possibly engender a different observation of aid effectiveness as well.Show less
