Research master thesis | Psychology (research) (MSc)
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Real-world natural behavior employs a range of frontal midline theta (FMθ)-related cognitive processes. Therefore, it is crucial to discover the natural behavioral correlated of fluctuations in FMθ...Show moreReal-world natural behavior employs a range of frontal midline theta (FMθ)-related cognitive processes. Therefore, it is crucial to discover the natural behavioral correlated of fluctuations in FMθ power. FMθ power has been investigated with a broad spectrum of behavioral tasks, each linked to a specific cognitive mechanism. However, the behavioral responses in those tasks cannot reflect natural behavior. This leaves a significant gap in our understanding of how these neuronal mechanisms translate into natural, complex, everyday behavior. This study bridges this gap through measuring the next-interval temporal dynamics of natural smartphone interactions. To quantify the complex real-world behavior, we are measured the next-interval temporal dynamics of natural smartphone interactions, using the recently introduced joint-interval distribution (JID). The JID represents the probability distribution of the occurrence of interaction interval k in conjunction with its next interval k+1. This method results in a 50x50 matrix where each pixel contains the probability of recorded interactions that occurred given a certain ITI (k) and consequent ITI (k+1). We measured simultaneous full-cap EEG and smartphone interactions during a one-hour session with 69 participants. The FMθ power and JID was calculated per two-minute bin per participant. We used robust regression of the two measures for each participant, and then applied a clustering method to account for multiple comparison. Four main findings emerge from the results: One, there are discernable behavioral correlates of fluctuations in FMθ power. Two, the fluctuations of FMθ power relate to specific temporal dynamics of natural smartphone behavior. Three, the behavioral correlates of fluctuations of FMθ power are more prominent in transitional than monotonous next-interval behavior. Four, there are individual differences in the behavioral correlates of FMθ power fluctuations. Overall, the results paints a multifaceted picture of the behavioral correlates of FMθ power, emphasizing both the complexity and the specificity of these relationships. The discovered natural behavioral correlates may extend existing theories on FMθ power’s role in cognition, specifically cognitive control, working and short-term memory, learning, performance, the DMN and adaptive motor control. Fluctuations in response times in cognitive assessment tasks may be transferable to the temporal dynamics of natural behavior. The discovery of the natural behavioral correlates of FMθ power fluctuations offer intriguing insights and new research opportunities.Show less
Research master thesis | Psychology (research) (MSc)
under embargo until 2024-08-01
2024-08-01T00:00:00Z
Causal beliefs about depression can shape patient behavior and treatment adherence and in the case of adolescent depression, causal beliefs of both depressed adolescents and their parents seem to...Show moreCausal beliefs about depression can shape patient behavior and treatment adherence and in the case of adolescent depression, causal beliefs of both depressed adolescents and their parents seem to be of equal importance. In this mixed-method study, we aimed to 1) qualitatively identify the causal beliefs of depression reported by clinically referred adolescents and their parents, and examine the discrepancies between mother-child and father-child pairs and to 2) quantitatively assess the relationship between these discrepancies and adolescent depression severity, and investigate whether this relationship was moderated by the adolescent’s attachment security with their parents. As part of the RE-PAIR project, a total of 34 adolescents, 34 mothers, and 26 fathers participated in interviews and completed questionnaires. The interview data was analyzed using thematic analysis in ATLAS.ti, and hierarchical regression analysis in SPSS was conducted to test the moderation hypothesis. The results revealed a total of 12 distinct causal beliefs, centered around relational issues, stressful family context, and inherent characteristics of the adolescent. We found high discrepancy levels (i.e. low agreement: 0-54%) between the reports of adolescents and their parents regarding these beliefs. However, these high discrepancies did not significantly relate to the severity of adolescent depression. While this study was the first to examine both adolescent and parental causal beliefs in a discrepancy-depression framework, further research is needed to understand the impact of discrepant perspectives on treatment outcomes and to explore the level of parental insight and understanding (e.g. good communication/ attachment security) for their adolescents’ perspective, despite differing views.Show less
Research master thesis | Psychology (research) (MSc)
closed access
Understanding the complex interactions between neurotransmitters and large-scale brain networks is crucial for unraveling the underlying neurochemical mechanisms of cognitive processes. Although...Show moreUnderstanding the complex interactions between neurotransmitters and large-scale brain networks is crucial for unraveling the underlying neurochemical mechanisms of cognitive processes. Although brain functions are modulated by a large number of neurotransmitters, one stands out for its key involvement in cognition: dopamine. This compound has been shown, although not consistently, to affect three of the main brain networks: the salience network (SN), the central executive network (CEN), and the default mode network (DMN). Specifically, an increase in dopamine has been often associated with an increase in intra SN-connectivity, resulting in a heightened negative coupling between the CEN and DMN. However, not only these results remain uncertain, but research in the field remains incomplete as until now, it has maintained a narrow focus. Thus, the present fMRI study aimed to expand on previous findings, by investigating the effects of dopamine on the SN, CEN and DMN during a working memory task. We recruited 30 healthy participants, all of which took part in two sessions, during which we manipulated their dopamine levels in the brain. To this end, in each session they received either a placebo or L-dopa, a precursor of dopamine known to increase the brain’s dopamine production and availability. During each session, participants underwent fMRI scanning, while performing a working memory task consisting of alternating working memory and rest blocks. Based on previous research, we hypothesized that dopamine would lead to a faster switch between the CEN and DMN when switching between working memory and rest blocks. In addition, we hypothesized that this faster switch would be driven by a higher intra SN connectivity. Results of paired permutation testing, as well as of a three-way ANOVA, revealed a lack of the expected dopamine-dependent changes. Dopamine did not significantly affect the switch between the CEN and DMN, nor it affected SN connectivity. These findings contradict previous literature, and call for further investigation of the dopaminergic modulation of these networks and their interactions.Show less
Research master thesis | Psychology (research) (MSc)
open access
Across clinical assessment tasks, a statistical model trained on the assessments of one person (a person’s model) has been shown to be more accurate than the person on which the model is based, the...Show moreAcross clinical assessment tasks, a statistical model trained on the assessments of one person (a person’s model) has been shown to be more accurate than the person on which the model is based, the Model-over-Person effect. Because the language that people use to express their state of mind is clinically meaningful, the objective of this study was to examine whether the Model-over-Person effect extends to language assessments as well as to identify conditions in which the effect occurs. The accuracy of the assessments of a person versus a person’s model was measured as their agreement with a reference standard (the mean assessment of multiple assessors) in two conditions: 1) the assessment of single words and 2) the assessment of texts. Artificial Intelligence based language assessments were employed to create the person’s model. No Model-over-Person effect occurred in the assessment of single words or all texts (N = 500 words/texts). A small Model-over-Person effect took place for all three assessors in the assessment of the longer texts (⩾ 50 words; dz = .39-.42; n = 23 texts). This effect be explained by the finding that a high amount of input data can make an assessment more prone to human error. Additionally, the relation between the accuracy and different assessment and language characteristics indicated that a person’s model could be more accurate in case of a low agreement among assessors and that the accuracy is not related to the confidence of the assessor in the assessment. The results show how computational language assessments can complement a person in accuracy and may support the use of computational language models as decision-support in clinical decision-making.Show less
Research master thesis | Psychology (research) (MSc)
closed access
Communication involves understanding the difference between our own perspective (visual perspective, beliefs, and knowledge) and that of an addressee. Previous research found that knowledge about a...Show moreCommunication involves understanding the difference between our own perspective (visual perspective, beliefs, and knowledge) and that of an addressee. Previous research found that knowledge about a speaker’s background (e.g., stereotypes, accent, etc.) affects online language processing in listeners. However, the role and automaticity of Theory of Mind (ToM) – the ability to attribute beliefs to someone - remains unclear. Typically, we expect individuals to speak according to their beliefs and perspectives. But what if their utterances mismatch with what we expect them to know? We designed a novel perspective-taking paradigm in a virtual environment, which manipulates an agent’s belief. We then recorded electroencephalographical data from participants, while they listened to the agent making statements either matching or mismatching their false or true beliefs. Specifically, we analyzed the N400: a component, which amplitude scales with the unexpectedness of a content word. We predicted that statements mismatching an agent’s true belief (e.g., seeing a car and saying “That’s a screwdriver”) would result in larger N400 components, compared to statements matching the true beliefs. We found strong evidence for this prediction. Further, we predicted that knowledge of an agent’s unawareness that the state of affairs has changed (i.e., a false belief) is considered when interpreting their statements. We found indirect evidence for this: statements matching their false beliefs do not elicit an N400. However, statements mismatching their false beliefs (e.g., agent says something they couldn’t have known) neither are marked by the N400. Results support ToM’s role in interpreting language.Show less
Research master thesis | Psychology (research) (MSc)
closed access
Negative social reactions to women’s sexual assault disclosure, including disbelief, victim-blaming, and negative character judgments have detrimental consequences for survivors’ mental and...Show moreNegative social reactions to women’s sexual assault disclosure, including disbelief, victim-blaming, and negative character judgments have detrimental consequences for survivors’ mental and physical health and willingness to report the assault. Negative social reactions to female sexual assault disclosure are more often shown by men than women. This effect may be stronger, the more men identify with their gender. Negative reactions to female sexual assault disclosure among men may correspond to possible consequences of two types of social identity threat that depend on gender identification levels. High-identified men may experience threat to the value of their group (value threat), and low-identified men may experience threat of being seen primarily in terms of their male group identity (categorization threat). In the present research, we investigated belief, fault attribution, trait ratings, perceived male heterogeneity, and perceived male stigma in response to women’s disclosure of being sexually assaulted, mugged, or in an accident with men among a mixed gender (Study 1; N = 139) and a male sample (Study 2; N = 79). Study 2 additionally assessed cardiovascular threat. Results indicated that men, compared to women, expressed less belief, higher fault attribution, more negative trait ratings, and more perceived male heterogeneity and male stigma. High-identified, compared to low-identified men, displayed more negative reactions, perceived more stigma against men, and perceived less male heterogeneity. This pattern was mostly reversed for women. Male gender identification was more strongly associated with negative trait judgments of women disclosing sexual assault compared to other experiences, especially regarding morality. Men exhibited higher cardiovascular threat levels when discussing women’s disclosure of sexual assault than of an accident. Contrary to our predictions, we did not find a mediation of social reactions through cardiovascular measures that was moderated by gender identification components. Across studies, men’s reactions were mostly consistent with social identity threat responses: High-identified men’s negative reactions and perceived male stigma indicated value threat, while low-identified men’s emphasis on male heterogeneity indicated categorization threat. Our results emphasize the value of a social identity threat perspective on social reactions to sexual assault disclosure and highlight potential for future investigations with cardiovascular threat measures.Show less
Research master thesis | Psychology (research) (MSc)
closed access
Given the practical importance of interpersonal trust in negotiations, scholars have increasingly given attention to the mechanism underlying the effect of trust and possible strategies, such as...Show moreGiven the practical importance of interpersonal trust in negotiations, scholars have increasingly given attention to the mechanism underlying the effect of trust and possible strategies, such as mediation, to handle low trust negotiations. However, research with direct mediator interventions in experimental settings has been rare. We sought to validate previous survey research on the effects of trust and a third-party mediator on negotiation outcomes, negotiator mindset, and perceptions of the negotiation. In our study we looked at the effects of a low trust or a high trust condition on dyadic level, as well as looking at the effect of the presence or absence of a mediator on how dyads negotiated. 38 participants, primarily female students from Leiden University, negotiated in a role-play scenario in a dispute as either a bar owner or a customer. Primary analyses showed no effects for trust on negotiation outcomes, mindset, or satisfaction. Due to severe limitations mediation was not analyzed. Exploratory findings showed that trust increased cooperative efforts and improved relationships, and that secondary agreements, agreements not on prices, were of importance in the negotiations. This study nuances the previously found effects of trust on negotiations and asks for more understanding of the underlying mechanisms and effects of trust.Show less
Research master thesis | Psychology (research) (MSc)
closed access
The power spectral density (PSD) exponent value, indicative of the brain's excitation and inhibition (E/I) balance, has been associated with cognitive fluctuations over time and show disruptions in...Show moreThe power spectral density (PSD) exponent value, indicative of the brain's excitation and inhibition (E/I) balance, has been associated with cognitive fluctuations over time and show disruptions in neurological disorders. Yet, how this balance influences real-world behavioral dynamics remains less explored. In this study, we examined the relationship between E/I and real-world behavioral dynamics. We captured spontaneous real-world behavioral dynamics from 68 participants using inter- touch intervals (ITI) on the smartphones during a 45–90-minute EEG session. Following EEG recordings, we computed the power spectral density (PSD) over the data and applied the FOOOF method to extract the E/I balance. We then analyzed the relationship between this E/I balance and the real-world behavioral dynamics, as indicated by ITI’s. We show that real-world behavioral dynamics and E/I are related but show a considerable amount of inter-individual variability. On average, behaviors occurring between 0.03 and 1 second were accompanied by an increase in excitation, while behaviors (between 1 and 3 seconds) showed an increase in inhibition. Moreover, we identified three distinct participant types, each demonstrating unique patterns of interaction between E/I balance and real-world behavioral dynamics. In conclusion, our study emphasizes the value of the JID as a tool capable of capturing the relationship between real-world behavior and E/I on a detailed scale. This level of detail provides a unique perspective that increases our understanding of how cognition plays a role in complex real-world behavioral dynamics.Show less
Research master thesis | Developmental Psychopathology in Education and Child Studies (research) (MSc)
closed access
Background and objective: Sex Chromosome Trisomy (SCT) refers to having an extra X or Y chromosome (XXX, XXY, XYY), which occurs in approximately 1-2 of 1000 children. In this study, social...Show moreBackground and objective: Sex Chromosome Trisomy (SCT) refers to having an extra X or Y chromosome (XXX, XXY, XYY), which occurs in approximately 1-2 of 1000 children. In this study, social attention, Theory of Mind (ToM) and neurobehavioral outcomes are investigated in preschool aged children with SCT compared to typically developing controls. Furthermore, the study aims to explore with a longitudinal design whether social attention and ToM in preschool aged children with SCT can be predictive of neurobehavioral outcomes one year later. Methods: In this study 71 children with SCT (aged 3-7) and 71 typically developing age matched controls participated. The Social Interaction Scanning (SIS) eye tracking paradigm was used to investigate social attention. ToM skills were measured with the ToM subtest of the Developmental NEuroPSYchological Assessment, second edition (NEPSY-II). Neurobehavioral outcomes were measured with the Social Responsiveness Scale, second edition (SRS-2), Strengths and Weaknesses of ADHD and Normal behavior (SWAN) and the Child Behavior Check List (CBCL) parental questionnaires respectively. Results: Results of the current study show a vulnerability for children with SCT in the domain of social attention to faces and eyes and ToM compared to typically developing controls. Findings are more pronounced for children aged 5-7 years old. Furthermore, children with SCT appear at increased risk for poorer neurobehavioral outcomes. Finally, results of the current study suggest that ToM may have a unique predictive value for social impairment over time, specifically in the domain of social communication and interaction. Secondly, social attention may have a unique predictive value for ADHD symptoms over time. Conclusions: Results indicate that screening of social cognitive functions (around the age of 5-7) and monitoring of neurodevelopmental pathways is important for clinical practice in SCT. In future research the efficacy of early tailored interventions targeting social cognitive skills in SCT can be investigated, to positively influence developmental outcomes of children with SCT.Show less
Research master thesis | Psychology (research) (MSc)
closed access
Objective: Childhood anxiety disorders are a widespread concern that may impede children’s development. Cognitive Behaviour Therapy (CBT) with exposure is considered an effective treatment for...Show moreObjective: Childhood anxiety disorders are a widespread concern that may impede children’s development. Cognitive Behaviour Therapy (CBT) with exposure is considered an effective treatment for childhood anxiety. After treatment, home practice helps children to develop skills that they learned during CBT. However, home practice is often challenging for children. Mobile health (mHealth) apps have the potential to facilitate home practice. We aimed to describe the development of the KiBA (Kids Beat Anxiety) app and test its usability. Method: In Study 1 (development phase), we included therapists (n = 5) and children (n = 8, aged 7- 14) to review app mock-ups during five meetings. IT-specialists incorporated the feedback multiple times. Next, two beta-tester groups tested the app and rated its usability. The first group tested the app for one hour at school (n = 14, mean age = 9.50), and the second group tested the app for one week at home (n = 8, mean age = 10.55). In Study 2 (clinical sample), children with a specific phobia (n = 8, Mage = 12.10) used the app for four weeks at home following CBT, and children and parents rated its usability. Results: Feedback led to multiple improvements (e.g., game elements, layout, colors, instructions). Usability ratings were both high in the beta-tester groups in the development phase (8.4/10 and 8.1/10) and the clinical sample (8.6/10 children and 8.1/10 parents). Children indicated they found the app easy, fun, and user-friendly. Conclusions: This study underlines the value of including end-users in the development of mHealth apps. The KiBA app (1) offers tools for children and their parents to practice exposure at home, and (2) helps therapists to monitor children’s progress.Show less
Research master thesis | Psychology (research) (MSc)
open access
Individuals with a lower socioeconomic status (SES) are at an increased risk for developing depressive symptoms. However, it has not been investigated whether this link is homogenous, or whether...Show moreIndividuals with a lower socioeconomic status (SES) are at an increased risk for developing depressive symptoms. However, it has not been investigated whether this link is homogenous, or whether specific depressive symptoms relate to SES differentially. In this thesis, I explored (1) which individual symptoms of depression are related to subjective social status (as a proxy for SES); (2) how specific indicators of SES are related to specific symptoms of depression; and (3) how the addition of stressors impacts the relations between SES indicators and depressive symptoms. I used data previously gathered from 448 students aged ≥18 at institutions of higher education in the Netherlands, as a part of the WARN-D study. Variables were assessed through a questionnaire that was administered online. I estimated three regularised partial correlation networks to explore shared variances among nine symptoms of depression, five indicators of SES, and seven stressors. The network analyses revealed that (1) subjective social status (as a proxy for SES) was negatively associated with guilt/worthlessness, depressed mood, anhedonia, trouble concentrating, and feeling tired, meaning that participants with higher scores on subjective social status had, on average, lower scores on these symptoms; (2) educational level (as one of multiple indicators of SES) was negatively associated with appetite disturbances, and the ability to get by financially was negatively associated with depressed mood, guilt/worthlessness, and appetite disturbances; (3) these associations diminished considerably or disappeared altogether when controlling for the stressor variables. Overall, all SES-depression associations were small in magnitude. The results suggest that patterns of depressive symptoms might differ between high-SES and low-SES individuals. Future research should explore the mechanisms behind these differences to guide prevention and intervention. My findings are consistent with previous research showing that symptom composite scores obscure important differences between individuals.Show less
Research master thesis | Psychology (research) (MSc)
open access
This study investigated whether suggestion and placebo effects can induce mystical experiences using the God Helmet, a placebo brain stimulation device. Seventy-nine participants wore the placebo...Show moreThis study investigated whether suggestion and placebo effects can induce mystical experiences using the God Helmet, a placebo brain stimulation device. Seventy-nine participants wore the placebo God Helmet for 45 minutes in sensory deprivation and were interviewed about their experience. A qualitative analysis showed that, although participants reported unusual experiences, these were distinct from their previous mystical experiences. Additionally, a permutation analysis revealed that participants rated the intensity of the God Helmet experience lower on average than their previous mystical experiences, suggesting that the God Helmet experiences are less intense. Nevertheless, the experiences induced by the God Helmet were reported as stronger than normal daydreaming and shared similarities with hypnagogic (falling asleep) states. In addition, a regression showed that individuals with more previous mystical experiences had more unusual experiences with the God Helmet and a higher Mysticism scale score, highlighting the importance of considering individual differences for understanding sensitivity to mystical-type experiences. Furthermore, as the God Helmet shows potential for inducing hypnagogic states within a 45-minute session, it has potential applications in sleep research and provides new avenues for investigating altered states of consciousness. However, as the God Helmet does not induce authentic mystical experiences with long-term positive effects, it is not an effective tool for investigating mystical experiences or applying them for therapeutic purposes.Show less
Research master thesis | Developmental Psychopathology in Education and Child Studies (research) (MSc)
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Children that show high levels of persistent aggressive and transgressive behavior have found to be at serious risk of exhibiting delinquent and criminal behavior during later adolescence and...Show moreChildren that show high levels of persistent aggressive and transgressive behavior have found to be at serious risk of exhibiting delinquent and criminal behavior during later adolescence and adulthood. However, a clear explanation of possible underlying neurocognitive mechanisms contributing to the increased risk of developing criminal behavior is lacking. Therefore, this thesis aims to contribute to, and encourage comprehensive and nuanced analysis of the issue of children at risk of later onset of criminal and delinquent behavior, and to offer insight into the most effective ways of promoting positive outcomes for both individual children and society. Specifically, in the current study self-efficacy served as a proxy for childhood agency, whereby the relation between self-efficacy, social competence, and the possible mediating role of Theory of Mind (ToM) was investigated. The data in this study was derived from a sample of 425 children, aged eight to twelve, from the Preventive Intervention Trajectory (PIT) project. Overall, the results of the present study did not offer substantiation for the proposed mediation model. In addition, the comparative analysis of self-efficacy based on gender revealed a relatively equal distribution and there was no significant difference in mean self-efficacy scores between boys and girls. Total IQ did however show significant relations, as it was associated with higher ToM scores and less social problems. This finding is consistent with previous studies and suggests that intelligence should be taken into consideration in research and intervention of children with transgressive and aggressive behavior problems. The results do not necessarily rule out the underlying influences of self-efficacy, ToM, and social problems on transgression and aggression. More research is necessary to confirm the results of this study an identify the underlying neurocognitive constituents of childhood agency.Show less
Research master thesis | Psychology (research) (MSc)
closed access
Observing emotions in others’ facial expressions is an important factor guiding social interaction. Observing others’ emotions elicits physiological arousal in the observer, which is reflected in...Show moreObserving emotions in others’ facial expressions is an important factor guiding social interaction. Observing others’ emotions elicits physiological arousal in the observer, which is reflected in increased pupil diameter (i.e., pupil dilation). The current study used pupil dilation as an index of physiological arousal to explore children’s responses to emotional facial expressions. More specifically, we investigated whether maternal symptoms of depression and/or anxiety were related to offspring’s pupil responses to negative (versus positive) facial displays irrespective of the child’s symptomology. A community sample of 87 mother- (M = 42.30, SD = 5.60, range = 27-57) child (M = 10.11, SD = 1.32, range = 7.2-12.9) dyads participated in the current study. Mothers and offspring reported on their depressive and anxiety symptoms via self-report questionnaires. Children’s pupil responses to angry, fearful, sad, and happy dynamic facial displays were measured during the dynamic emotions task using eye-tracking. Results revealed that maternal depressive symptoms were not related to child pupil responses to negative (versus positive) faces. Higher levels of maternal anxiety, however, were linked to stronger child pupil responses to fearful and sad faces than to happy faces. In turn, child pupil responses to angry (versus happy) faces did not statistically differ as a function of maternal anxiety. These findings persisted after accounting for the link between child anxiety symptoms and child pupil responses. Therefore, the way typically developing children react to negative versus positive emotional faces in later childhood appears to be related to maternal levels of anxiety, but not to maternal levels of depression. This points to the importance of exploring maternal anxiety symptoms as a potential risk factor for the development of negativity biases in offspring across the general population.Show less