Extinction learning, a process where conditioned responses to a previously threatening stimulus are reduced, is a foundational process of many therapeutic interventions such as exposure therapy....Show moreExtinction learning, a process where conditioned responses to a previously threatening stimulus are reduced, is a foundational process of many therapeutic interventions such as exposure therapy. Individuals with a history of childhood maltreatment may have impairments in extinction learning processes, potentially affecting the efficacy of these therapies for this population. Investigation of this relationship between childhood trauma and extinction learning can better the development of effective therapeutic strategies for those with trauma histories.. The relationship between childhood maltreatment and extinction learning in healthy volunteers was investigated to explore whether individuals with a history of childhood maltreatment exhibit different patterns of threat extinction compared to those without exposure to maltreatment. Using a cross-sectional design, data was analyzed from healthy adult volunteers, combined from two studies (n= 73), those with and without exposure to childhood maltreatment, divided into two groups based on their Childhood Trauma Questionnaire (CTQ-SF) scores. Participants completed an extinction paradigm, during which skin conductance responses (SCR) and heart rate (HR) were measured. The results showed that CTQ-exposed participants exhibited heightened HR to CS+ and lower responses to CS- during extinction trials compared to non-exposed individuals, revealing distinct physiological reactions. There were no additional significant differences in SCR and HR extinction and re-extinction patterns between the maltreatment-exposed and non-exposed groups. These findings suggest that childhood maltreatment may not necessarily impair extinction learning in a healthy adult population. Further research with longitudinal designs and clinical populations is needed to further understand how maltreatment experiences may influence extinction processes.Show less
This study investigates how perceptions of status and warmth of help-seekers affect the willingness of help-givers to offer help as well as the type of help they offer (autonomyoriented help...Show moreThis study investigates how perceptions of status and warmth of help-seekers affect the willingness of help-givers to offer help as well as the type of help they offer (autonomyoriented help/dependency-oriented help). Data were collected using a scenario approach (N = 205) in an experimental study, which simulated a debt assistance setting in a municipality. The variables Status (low/high) and Warmth (low/high) were investigated in a betweensubjects design. Participants completed an online survey on perceived warmth, status, and locus of attribution of a help-seeker and indicated their willingness to help as well as the type of help. It was hypothesized that warmth perceptions of help-seekers would influence the likeliness to help, that status perceptions would influence the locus of attributions as well as the type of help and that the effect between status and type of help would be mediated by the locus of attributions. The study did not find support for these hypotheses. However, exploratory analyses revealed a significant positive effect of both Status and Warmth on perceived competence, and significant correlations between locus of attributions and likeliness to help, autonomy and dependency-oriented help, and emotions (admiration/envy/pity) and type of help. These findings underline the role of stereotypes and biases in influencing helping behavior, emphasizing the need for further investigations of helping mechanisms.Show less
In this research, a recently proposed renormalization group approach for networks to the case of random directed graphs is being generalized: we present a scale-invariant description of directed...Show moreIn this research, a recently proposed renormalization group approach for networks to the case of random directed graphs is being generalized: we present a scale-invariant description of directed networks containing reciprocated edges. This allows us to neglect several strong assumptions that are currently necessary to renormalize directed networks such as financial transaction networks. As an application, a model of ING’s transaction data has been derived across multiple coarse-grained partitions. In this article we provide detailed information on how this particular model has been structured and how its parameters are obtained. We show how we can use this model to determine the expected cumulative degree and weight distributions of ING’s transaction network across multiple coarse-grained partitions of the network which we will compare to the empirical degree and weight distributions, respectively.Show less
Despite the deleterious effects feelings of loneliness can have on mental and physical health, factors that may mitigate feelings of loneliness are understudied in youth with autism spectrum...Show moreDespite the deleterious effects feelings of loneliness can have on mental and physical health, factors that may mitigate feelings of loneliness are understudied in youth with autism spectrum disorder (ASD). This study focused on the role of friendships in feelings of loneliness in autistic students and their allistic peers. We aimed to examine the extent to which autistic and allistic students differ in the number of perceived, received, and reciprocal friendships, how these three types of friendships are related to feelings of loneliness in school, and how autistic and allistic (without ASD) students differ in this relation. Forty-one autistic students (92,7% male, M age = 10.17, SD = 1.0) were compared with 44 allistic students (43,2% male, M age = 11.14, SD = 1.0), both from special education schools. Participants completed the Children’s Loneliness Scale and provided names of their best friends (up to five names). Results indicated that autistic students did not have fewer perceived, received, and reciprocated friendships than their allistic peers, and did not differ in feelings of loneliness with their allistic peers. Also, the number of received and reciprocal friendships did not contribute to feelings of loneliness, but having more perceived friendships was associated with less feelings of loneliness, to the same extent in the two groups. In conclusion, the findings showed that autistic students can form friendships that fulfill their social needs when in a suitable environment, and the perception of having friends could be the most important for both groups to feel a sense of connectedness in school. Thus, for regular schools, it may be helpful to learn from special education schools to facilitate the best environment for all students to form and maintain friendships.Show less
Childhood trauma is strongly associated with the risk of developing various physical and mental health disorders, such as depression and eating disorders. Three-quarters of chronically depressed...Show moreChildhood trauma is strongly associated with the risk of developing various physical and mental health disorders, such as depression and eating disorders. Three-quarters of chronically depressed people have experienced childhood trauma. Depression, described as a disorder of impaired emotion regulation, is linked to various disordered eating behaviors. Emotional eating, overeating in response to negative affect, is viewed as a maladaptive emotion regulation strategy and may contribute to the creation, maintenance, or worsening of depressive symptoms. This study aimed to examine the association between childhood trauma and emotional eating in a large sample of adults with current or past depression. Given that women show higher prevalence in disordered eating, we tested for a moderation effect of gender. Additionally, we explored how separate subtypes of trauma are related to emotional eating. We used data from the Netherlands Study of Depression and Anxiety (NESDA), an ongoing naturalistic longitudinal cohort study. The sample consisted of 1,353 individuals (818 women, 355 men) aged 26-75 years (M = 51.30). To assess childhood trauma, depression, and emotional eating, we used the Comprehensive Trauma Interview, CIDI 2.1, and the Dutch Eating Behaviour Questionnaire. As hypothesized, childhood trauma was predictive of emotional eating. Although women showed higher levels of emotional eating, no moderation effect of gender was found. As the first study in the Netherlands to examine these relationships, the results highlight the importance of assessing childhood trauma in any psychopathology and emphasize the need to screen for emotional eating in the depressed population to better inform treatment options.Show less
Psychotherapy necessarily involves a relationship between a therapist and a client. In examining this relationship, researchers address what is referred to as the therapeutic alliance. Contemporary...Show morePsychotherapy necessarily involves a relationship between a therapist and a client. In examining this relationship, researchers address what is referred to as the therapeutic alliance. Contemporary research established this alliance as an important common factor that has a significant effect on therapeutic outcomes. An alliance rupture is defined as a breakdown in agreement on therapeutic goals or tasks or of the therapeutic bond. Such ruptures are a near inevitable aspect of the therapeutic process. Distinct from existing meta-analyses which explored the relationship of rupture repairs on outcomes, the present research examines the effect that alliance ruptures themselves, identified through direct measures, have on therapeutic outcomes. Five studies were included in the meta-analysis (N = 366). A multilevel model was used to determine an aggregate effect size of ruptures on outcome across the included studies. In agreement with the paper’s hypothesis, the analysis showed a small but consistent positive relationship between ruptures and therapeutic outcomes where increased ruptures correlated with greater impairment in outcomes.Show less
Hashimoto’s thyroiditis is a common autoimmune disorder. Hashimoto’s thyroiditis patients may experience cognitive impairments such as memory problems, even after receiving LT4-monotherapy. This...Show moreHashimoto’s thyroiditis is a common autoimmune disorder. Hashimoto’s thyroiditis patients may experience cognitive impairments such as memory problems, even after receiving LT4-monotherapy. This study investigates the memory performance of Hashimoto’s thyroiditis patients with residual symptoms after receiving LT4 monotherapy, utilizing participants from the T3-4 Hypo Trial. Memory performance was assessed using the Rey Auditory Verbal Learning Test (RAVLT) 15-Word Task and the data were compared to normative data from the Advanced Neuropsychological Diagnostics Infrastructure Norms (ANDI-Norms). Results indicate that Hashimoto’s thyroiditis patients do not significantly perform different to the general population. This study investigated whether age and sex are potential predictors of memory performance. These factors showed no significant results suggesting that they are not related to memory performance. However, this study does highlight limitations such as possible comorbidity, uneven distribution of sex and education levels that need consideration. Future research is advised to better understand the complex relationship between Hashimoto’s thyroiditis and cognitive function. This study contributes to the broader understanding of the relationship between cognitive function and Hashimoto’s thyroiditis and underscores the need for future research to develop effective and/or improve existing clinical management strategies.Show less
The current study investigated the role of early maladaptive schema (EMS), particularly the schemas subjugation and self-sacrifice in mediating the relationship between adverse childhood...Show moreThe current study investigated the role of early maladaptive schema (EMS), particularly the schemas subjugation and self-sacrifice in mediating the relationship between adverse childhood experiences (ACE) and transdiagnostic somatic symptoms. Through convenience sampling, participants’ demographic data, EMS score (YSQ-3), ACE score (ACE questionnaire), and presence of transdiagnostic somatic symptoms (DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Measure) were measured. The total scores of subjugation and self-sacrifice, ACE, and transdiagnostic somatic symptoms were respectively summated, then analysed through mediation analysis. Participants were (N = 131) students of Leiden University from the age of 18 years old (M = 19, IQR = 2), comprising of 91.2% female and 8.8% male. Through the analysis, it was found that subjugation and self-sacrifice together significantly mediate the relationship between ACE and transdiagnostic somatic symptoms (b = .314, p = .003). The indirect effect was found to have mediated 55.6% (b = .175, p = .002) of the relationship. Moreover, exploratory analyses indicated that individually, subjugation and self-sacrifice also successfully mediated this relationship. This finding further strengthens the existing argument that following ACE, particular behavioral stress-response may lead to transdiagnostic somatic symptoms in later life. In this case, the schemas subjugation and self-sacrifice were found to be crucial in this relationship. Thus, providing a deeper look into the developmental trajectory of the ACE, EMS, and transdiagnostic domains and may aid clinicians in recognizing and targeting schemas related to transdiagnostic somatic symptoms.Show less
Background: Previous studies have shown that the transition to parenthood elicits stress in parents, which may have negative consequences for their children, especially in their first years of life...Show moreBackground: Previous studies have shown that the transition to parenthood elicits stress in parents, which may have negative consequences for their children, especially in their first years of life. Yet, knowledge of paternal stress and its risk factors is scarce, because fathers have been neglected in parenting research. In the current study we, therefore, examined whether a history of child maltreatment, a thoroughly studied risk factor for stress in mothers, predicted parenting stress in fathers, making a clear distinction between neglect and abuse. Additionally, exploratory analyses were run to investigate the possible role of paternal protective tendencies. Method: First-time fathers with children up to three years old were recruited via social media platforms and via clinical facilities that offer perinatal care to fill out an online questionnaire. Results: A total of 210 fathers participated, who were mainly highly educated (72,4% bachelor’s degree or higher). Findings showed a significant positive association between childhood neglect and parenting stress. No mediating or moderating role of parental motivation for protection was found, however, a direct positive association was found between childhood abuse and parental motivation for protection. Conclusion: Current results underscore the importance of supporting fathers with a history of neglect in the early postnatal period and highlight the importance of distinguishing different types of childhood maltreatment. Furthermore, it suggests that fathers have a higher motivation to protect their children after experiencing childhood abuse, emphasizing the importance of more research into the possible overprotection tendencies of abused fathers. Longitudinal and experimental research is needed to support these findings and to unravel the mechanisms that cause paternal stress and factors that may buffer the negative consequences of childhood maltreatment.Show less
Objective. Neurofibromatosis type 1 (NF1) is a rare autosomal dominant single-gene disorder, primarily characterized by multiple (sub)cutaneous neurofibromas and café-au-lait macules. The cognitive...Show moreObjective. Neurofibromatosis type 1 (NF1) is a rare autosomal dominant single-gene disorder, primarily characterized by multiple (sub)cutaneous neurofibromas and café-au-lait macules. The cognitive profile of children with NF1 is hypothesised to be associated with deficits in three domains; visuospatial ability, executive function, learning and their interdependency. Between ages 11 and 15 years, an increase in PIQ was found in children with NF1. Because visuospatial abilities are strongly related to the level of PIQ as measured with the WISC-III-NL, the objective of this study was to find if improvement in visuospatial abilities in this course of age predicts this progress in PIQ. Methods. In a longitudinal design, 31 children with NF1 were assessed with the WISC-III-NL and a standardised battery of neuropsychological assessments at average age 11 and 15. In the statistical analyses the scores on the subtests of the WISC-III-NL constituting PIQ at age 11 and 15 were compared with paired t-tests and a repeated measures ANOVA. Next, five multivariable linear regression analyses were conducted with the increase in PIQ as the dependent variable and five neuropsychological constructs (visual and auditory attention, visuospatial ability, processing speed and fine motor skills) as the predictors. Results. Picture arrangement was the only WISC-III-NL subtest to increase between age 11 and 15, d = 1.04, p < .001. The repeated measures ANOVA resulted in a difference in improvement between the five WISC-III-NL subtest scores, p < .001. Visuospatial ability was the only neuropsychological construct that predicted the increase in PIQ, b = 1.22, p = .005. There was no correlation between improvement in picture arrangement and improvement in visuospatial ability. Conclusions. Improvement in visuospatial ability appears to predict increase in PIQ in children with NF1 between age 11 and 15. Further investigation is required to determine if these findings are replicable in larger sample sizes. Additionally, there is further research needed to explore variances in the amount of improvement observed across different visuospatial tasks. It may be possible that progress in executive function effects improvement in some visuospatial tasks. Implications are that executive functioning must be taken into account when interpreting (visuospatial) results from neuropsychological assessments in children with NF1, both in science and in the clinic.Show less
This experimental study used a 2 (social motives; pro-social vs. pro-self) x 2 (gender of the experimenter; female vs. male) design to examine the impact of social motives and gender stereotype...Show moreThis experimental study used a 2 (social motives; pro-social vs. pro-self) x 2 (gender of the experimenter; female vs. male) design to examine the impact of social motives and gender stereotype activation on the negotiating behaviour of female leaders in online group negotiations. A sample of 95 female participants, ranging from 20 to 70 years old and with various educational backgrounds, participated in an online group negotiation experiment. The participants negotiated against two fake counterparts. Their social motives were to either negotiate for themselves (pro-self) or for the group (pro-social) and they negotiated in an environment where gender stereotypes were activated through the gender of the experimenter. Results showed that neither social motives nor gender stereotype activation significantly impacted the negotiating behaviour of the female leaders. However, participants' social motives were more strongly influenced when a female experimenter led the experiment. These findings suggest that women may be more responsive to instructions from other women. Additionally, this study underscores the need to further explore the underlying factors affecting women's negotiation outcomes.Show less
While amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s disease (AD) are primarily defined by cognitive deficits, studies have demonstrated that motor impairments can precede cognitive...Show moreWhile amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s disease (AD) are primarily defined by cognitive deficits, studies have demonstrated that motor impairments can precede cognitive symptoms by several years in these conditions. However, it is uncertain if the ability to learn sequences of movements is also impaired in this population. Therefore, this study investigated whether aMCI and AD affect motor sequence learning abilities, and how such abilities are related to AD biomarkers. The sample included 33 individuals with aMCI, 28 with AD, and 52 healthy controls (HCs). All groups completed a motor task consisting of performing a sequence of button presses, alternated with random blocks. Reaction time, coefficient of variation, and learning rates were obtained from the task. Participants also completed a series of cognitive tests to assess memory, visuospatial abilities, processing speed, language, and attention. Additionally, the following biomarkers for AD were assessed: amyloid beta via PET imaging, hippocampal volume via structural MRI, and number of e4 alleles via APOE genotyping. ANOVAs showed that AD participants had longer and more variable reaction times, followed by aMCI individuals, and with HCs having the shorter and more consistent reaction times. No significant differences in sequence learning rate were observed between groups. Exploratory analyses revealed that aMCI/AD had significantly slower initial learning rate than HCs. Linear regressions showed associations of slower reaction times with smaller hippocampal volume, and of higher coefficients with higher amyloid deposition. Poisson regressions revealed no significant correlations between motor sequence learning and APOEe4 allele count. Akaike Information Criterion (AIC) results indicated that combining cognitive test with motor measures improves the prediction of AD biomarkers. Overall, AD and aMCI individuals showed impairments in general motor performance but relatively preserved motor sequence learning abilities, with some deficits in initial rate of learning. Moreover, statistical model comparison suggested that adding motor sequence learning measures to neuropsychological assessment tools enhanced the prediction of AD biomarkers. As such, future studies should explore the value of integrating motor sequence learning measures in the assessment and tracking of AD/aMCI.Show less
Background: This study on gut feelings investigates the correlation between microdiversity in the gut and cognitive reactivity in the brain, with sex as a potential moderator. Research on potential...Show moreBackground: This study on gut feelings investigates the correlation between microdiversity in the gut and cognitive reactivity in the brain, with sex as a potential moderator. Research on potential correlations and moderators is relevant to gain further insight into the networks involved in the gut-brain axis. The findings can influence treatment approaches in the field of clinical psychology to a greater focus on the gut- brain axis. Two hypotheses were examined: 1) a higher microdiversity in the gut is correlated with less emotion regulation difficulties, and 2) there are sex differences in the correlation between microdiversity and emotion regulation. Methods: This research was an observational between-subjects design with a total number of 75 participants. The primary outcome was the alpha score, assessed with the Shannon Index, which gives insight into individual microdiversity. The Difficulties in Emotion Regulation Scale was used to assess self-reported difficulties in emotion regulation to have insight into individual cognitive reactivity. Sex was conceptualised as the moderator variable. A correlational analysis for alpha scores and DERS scores was carried out, followed by a multiple regression analysis, which tested for a moderation with the variable sex. Results: There was no evidence for a negative correlation between high microdiversity and few emotion regulation difficulties. Sex did not have a significant moderation on this correlation either. Implications: Further research is needed on the gut-brain axis and sex differences in gut microdiversity and emotion regulation to adapt the treatment of stress-related disorders such as post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), or other anxiety-related disorders from a cognitive- to a more holistic approach.Show less
Loneliness affects both autistic and non-autistic children. Nevertheless, differences exist in the prevalence and characteristics of loneliness experienced by these two groups, especially in school...Show moreLoneliness affects both autistic and non-autistic children. Nevertheless, differences exist in the prevalence and characteristics of loneliness experienced by these two groups, especially in school settings. This study investigated how four school environment factors, i.e., physical connection, perceived emotional connections, received emotional connections, and recess enjoyment impact loneliness in school-aged children, focusing on the differences between autistic and non-autistic children. Conducted in 2 Dutch special education primary schools, this cross-sectional, between-group study included 104 students (Μ age = 10.4, age range: 6.8 – 14 years): 47 autistic (Μ age = 10.2) and 52 non-autistic (Μ age = 11.4). Loneliness levels were measured with the self-report questionnaire Children’s Loneliness Scale (CLS). For physical connection, the total time children spent in social contact during school recess was measured with proximity sensors (Radio Frequency Identification Device, RFID). Perceived emotional connections was measured with friendship nomination and received emotional connections with the “Like to play” (LITOP) questionnaire. Recess enjoyment was measured with Lunchtime Enjoyment of Activity and Play Questionnaire (LEAP). A regression analysis measured the relationship between feelings of loneliness and the four school environment factors, and the moderating role of autism. An independent sample t-test compared differences between groups for all variables. The results showed a significant relationship between physical connection and loneliness (β = -.409, t = -3.040, p = .003) and recess enjoyment and loneliness (β = .333, t = 2.690, p = .009). Autism moderated the impact of physical connection on loneliness: increased physical connection is associated with reduced loneliness in non-autistic children but heightened loneliness in autistic children (β = .596, t = 2.236, p = .028). Lastly, levels of physical connection (t (97) = 3.393, p = .001) were significantly lower in autistic (M = .539, SD = .221) than in non-autistic children (M = .695, SD). Our findings highlight the importance of understanding the distinct social needs and experiences of social interactions of autistic children. Policymakers and educators should prioritize gaining a deeper understanding of these differences between autistic and non-autistic children in order to develop more effective programs. With this knowledge, tailoring interventions specifically for autistic children can more effectively address loneliness.Show less
