This paper investigates the effect of nocebo suggestions on food craving levels and explores whether personality traits, specifically neuroticism and impulsivity, moderate this impact. The study...Show moreThis paper investigates the effect of nocebo suggestions on food craving levels and explores whether personality traits, specifically neuroticism and impulsivity, moderate this impact. The study was conducted using a sample of 21 volunteers which were recruited from Leiden University, and used a randomised controlled trial design. The two groups that were used in the analysis were control and nocebo groups (increase hunger). Nocebo group participants received a sham vagus nerve stimulation and were exposed to suggestions that this stimulation will increase their hunger. Food craving was measured using a Visual Analogue Scale at different time points throughout the experiment, and self-report inventories were used to assess neuroticism and impulsivity. A repeated measures Analysis of Variance (ANOVA) and a moderation analysis were performed to analyse the data. The results showed significant changes in craving intensity, F(3, 57) = 11.14, p < .001, with higher craving levels in the control group compared to the nocebo group. Neither neuroticism F(3, 17) = 0.37, p = .77, nor impulsivity, F(3, 17) = 2.11, p = .14, were significant in moderating the relationship between nocebo suggestions and food cravings. However, impulsivity independently showed a significant negative effect on craving ratings, where higher impulsivity was related to lower food cravings, b = -11.07, t(df) = -2.18, p = .04. The study’s limitations included a small sample size and ambiguous definitions of nocebo effects, which could have affected the results. Future research should focus on exploring other personality traits to deepen our understanding of their effect on nocebo suggestions and food cravings.Show less