Objective: In 2023, 44% of 32.000 Dutch students reported depressive or anxiety symptoms. This research investigated the relationship between academic stress and depressive symptoms among students...Show moreObjective: In 2023, 44% of 32.000 Dutch students reported depressive or anxiety symptoms. This research investigated the relationship between academic stress and depressive symptoms among students and examined whether sleep quality mediates the association between academic stress and depressive symptoms. Methods: A cross-sectional design was employed, involving N = 315 Dutch students. (mean age = 20.8 (SD = 2.5), 78.4% women). Participants completed questionnaires measuring academic stress, sleep problems, and depressive symptoms. Results: Linear regression analyses indicated that higher academic stress was significantly associated with more depressive symptoms (B = .217, p < .001) and poorer sleep quality (B = .083, p < .001). Additionally, a poorer sleep quality was positively associated with more depressive symptoms (B = .873, p < .001). Mediation analysis confirmed that sleep quality partially mediated the relationship between academic stress and depressive symptoms. Conclusion: These findings suggest that academic stress contributes to depressive symptoms partly through its impact on sleep quality. This study highlights the importance of addressing sleep quality in interventions aimed at reducing the negative mental health effects of academic stress. More extensive and longitudinal research is advised to further investigate the underlying mechanisms of the correlations found in this study. Future research should focus on developing and testing stress management interventions that also target sleep problems, to prevent depressive symptoms in student populations.Show less
The global prevalence of Alzheimer’s disease is expected to rise from 50 to 152 million cases by 2050 due to the limited availability of therapeutic and preventive strategies and ageing populations...Show moreThe global prevalence of Alzheimer’s disease is expected to rise from 50 to 152 million cases by 2050 due to the limited availability of therapeutic and preventive strategies and ageing populations. Although digital tools can address the growing gap between healthcare supply and demand, their implementation is difficult, and personal factors can influence individuals’ intention to use such tools. Thus, this study explores the relationship between various personal factors, as self-reported by healthy individuals (N = 507) who are part of a brain research registry, and their intention to use and promote using digital tools in the context of brain health and dementia. According to the hypothesis formulated for the research, higher financial scarcity, lower educational attainment, and lower employment status predict lower intention to use and promote digital tools for brain health. The study examined four distinct digital tools: (1) MijnBreincoach (a prevention tool), (2) cCog (a diagnostic tool), (3) ADappt (a patient- orchestrated care tool), and Neurokeys (a prediction tool). It was found that Neurokeys exhibited the highest score for intention to use but the lowest score for intention to promote. In addition, medium and high educational attainment predicted higher behavioral intention to use MijnBreincoach, while the most beneficial (i.e., most secure, stable, and safe) employment status predicted higher intention to promote MijnBreincoach and cCog. In conclusion, it is important to recognize differences in intention to use and promote different types of digital tools across potential users and the influence of personal characteristics on the intention to use and promote digital tools for brain health. During the development of a digital tool, it is recommended to consider which target audience would derive the greatest benefit from it and tailor it accordingly.Show less
This 3-wave study aims to examine the relationship between cognitive empathy (awareness and understanding of another’s emotion), affective empathy (experience of emotions consistent with those of...Show moreThis 3-wave study aims to examine the relationship between cognitive empathy (awareness and understanding of another’s emotion), affective empathy (experience of emotions consistent with those of the observed person), and self-perception of close friendships (one’s perception of the ability to form and maintain close friendships), both directly and indirectly through prosocial behavior (voluntary behavior intended to benefit another person) from late childhood to early adolescence. Participants were 127 adolescents aged between 10 and 14 years old who reported on their empathy, prosocial behavior, and self-perception of close friendships in three consecutive years, respectively. Simple mediation analyses revealed that cognitive and affective empathy did not have a significant positive effect on adolescents’ self-perception of close friendships two years later. Considering these findings, prosocial behavior was not found to be a mediator between adolescents’ cognitive or affective empathy and their self-perception of close friendships from late childhood to early adolescence. Moreover, cognitive and affective empathy did not significantly predict prosocial behavior one year later, whereas prosocial behavior did significantly predict the self-perception of adolescents’ close friendships one year later. These results underline the significance of developing tailored intervention programs targeting prosocial behavior to foster adolescents’ self-perception as close friends, a competence that is crucial during this developmental period considering the greater influence of peers.Show less
There are numerous people that experience financial hardship. It is important that they get support to get financially back on track. However, they often refrain from seeking help, likely due to...Show moreThere are numerous people that experience financial hardship. It is important that they get support to get financially back on track. However, they often refrain from seeking help, likely due to the shame associated with their financial situation (Keizer, 2016; Plantinga, 2019). This shame hinders their ability to adopt problem-focused coping strategies and consequently improve their financial circumstances (De Hooge et al., 2010). However, shame resilience shows a promising role in addressing this issue. It involves reducing feelings of entrapment, powerlessness, and isolation, thereby managing feelings of shame in a way so that enables people to effectively deal with their situation (Brown, 2006). This study investigates the effectiveness of shame resilience interventions in increasing communication between creditors and debtors. We conducted an experiment involving participants in debt and manipulated creditor letters to increase shame resilience. Results indicate that shame resilience interventions significantly increase willingness to contact creditors and improve the perceived trustworthiness of the company. These findings suggest that applying shame resilience interventions can assist people in taking the first step toward seeking help to address their debt.Show less
Gezonder eten: een doel dat velen van ons nastreven, maar vaak lukt het niet dit gedrag vol te houden. Op dat moment vindt er een terugval plaats, ook wel een setback genoemd. Na het ervaren van...Show moreGezonder eten: een doel dat velen van ons nastreven, maar vaak lukt het niet dit gedrag vol te houden. Op dat moment vindt er een terugval plaats, ook wel een setback genoemd. Na het ervaren van een setback wordt het moeilijker een gedragsdoel vol te houden. Deze studie onderzoekt waarom dit moeilijk wordt door de relatie tussen de ervaren setbacks tijdens het volgen van een dieet en maintenance self-efficacy te analyseren, met subjectief succes als mogelijke mediator. Met een online vragenlijst (N= 74) zijn de ervaren setbacks, maintenance self-efficacy en subjectief succes uitgevraagd. De vragenlijst had een cross-sectioneel, between-subjects design. De antwoorden op de vragenlijst zijn geanalyseerd met lineaire regressieanalyses en met een mediatie analyse. De resultaten lieten een significante negatieve relatie zien tussen de ervaren setbacks en maintenance self-efficacy. De relatie tussen de ervaren setbacks en subjectief succes was significant negatief, maar de relatie tussen subjectief succes en maintenance self-efficacy was niet significant. Echter, de resultaten lieten zien dat de ervaren setbacks weldegelijk negatief gerelateerd waren aan maintenance self-efficacy, en dat subjectief succes een negatieve mediërende rol in deze relatie kan hebben. Samengevat, de resultaten suggereren dat de ervaren setbacks kunnen zorgen voor een afname in maintenance self-efficacy en subjectief succes, wat weer zou kunnen leiden tot een toename in het ervaren van setbacks. Deze resultaten hebben gezorgd voor nieuwe inzichten, maar meer onderzoek is nodig naar andere mediërende factoren zoals recovery self-efficacy om het setback effect beter te kunnen begrijpen.Show less
As more environmental challenges arise, pro-environmental engagement becomes increasingly important. While sustainable diets are widely acknowledged for their ecological benefits, the interplay of...Show moreAs more environmental challenges arise, pro-environmental engagement becomes increasingly important. While sustainable diets are widely acknowledged for their ecological benefits, the interplay of social-emotional factors shaping such choices remained relatively underexplored. This study explored the interplay between guilt proneness, emotional support from best friends, and open- mindedness and their influence on young adults’ pro-environmental dietary choices. These variables were selected for their distinct impacts on decision-making processes and behavioural intentions, as guilt proneness motivates alignment with moral values, emotional support provides social reinforcement and validation, and open-mindedness encourages adoption of atypical diets. Plant-based diets involve (mostly) excluding meat including variations like flexitarian and pescetarian diets, while vegetarian diets exclude meat, and vegan diets exclude meat and animal-derived foods and products. The dietary choices in this study rank from the least to the most sustainable diet, being omnivores, plant-based, vegetarian, and ultimately, vegan. The cross-sectional design incorporated 213 individuals aged 17 to 26 from multiple genders and nationalities. The multiple stages assessment included a 45-minute online survey that employed specific tests to assess the factors. Dietary choice was assessed using the Dietarian Identity Questionnaire, guilt proneness using the Test of Self-Conscious Affect–3, emotional support from best friends using the Official short version of the Network Relationship Inventory, and open-mindedness using the Big Five Inventory-2. The multiple regression analyses indicated that guilt proneness, emotional support from best friend, open-mindedness, and the three-way interaction of these variables were non-significant predictors of dietary choice. These results diverged from initial hypotheses, emphasizing the need for exploration within different contexts and populations. The study's strengths included its cross-sectional design encompassing multiple nationalities and genders, and the thorough validation of statistical assumptions. However, the questionable to low reliability of some measures and the unequal gender distribution possibly affected the generalizability of the findings. Additional factors that may influence dietary choices among young adults, including cultural norms, socioeconomic status, anticipated pride, and peer influence, should be incorporated in future research. Interventions aimed at promoting pro- environmental dietary choices among young adults must adopt a holistic approach, considering individual, social, and environmental factors to facilitate long-term behaviour change.Show less
Primary progressive aphasia (PPA) is a form of early-onset dementia, characterised by a gradual decline in language abilities. PPA comprises three different subtypes with each subtype presenting...Show morePrimary progressive aphasia (PPA) is a form of early-onset dementia, characterised by a gradual decline in language abilities. PPA comprises three different subtypes with each subtype presenting unique linguistic impairments: nonfluent/agrammatic (nfvPPA), semantic (svPPA), and logopenic (lvPPA) PPA. However, diagnosing PPA in general, and specifically these variants, currently remains clinically challenging. To address this, the Mini Linguistic State Examination was adapted to the Dutch language (MLSE-NL). The MLSE-NL is a screening tool to evaluate language deficits related to PPA, measuring five different domains: motor speech, phonology, semantics, syntax, and working memory. This study aimed to validate and determine the effectiveness of MLSE-NL in distinguishing between PPA variants. A cross-sectional study was conducted with 99 participants, including 21 patients diagnosed with PPA and 78 cognitively healthy controls. A psychometric evaluation of the MLSE-NL was performed to evaluate the reliability and validity of the test. Furthermore, differences in performance on the MLSE-NL across PPA variants and the control group were analysed. Results showed that the MLSE-NL demonstrated robust psychometric properties, exhibiting high inter-rater reliability and strong convergent validity compared to other validated language tests. Significant differences were observed in the MLSE-NL total and subdomains scores between patients with PPA and control groups. Patients with PPA exhibited lower total scores and domain-specific scores on the MLSE-NL compared to cognitively healthy controls. Notably, within the motor speech and working memory domains, significant differences were observed within the PPA subtypes; nfvPPA, svPPA and lvPPA. No significant differences were found in the other domains. The findings of the current study are in line with outcomes from the original English version of the MLSE. Results showed that the MLSE is robust for use in another language and cultural context. When interpreting the results of the current study, the small sample size should be taken into account. In conclusion, the MLSE-NL emerges as a reliable and valid instrument for diagnosing and distinguishing PPA variants within the Dutch-speaking population. Future research with larger samples is necessary to validate these findings and expand the normative data.Show less
Placebos have been shown to affect both subjective experiences and physiological markers. However, their influence on defensive responses to threat has yet to be investigated. This study examines...Show morePlacebos have been shown to affect both subjective experiences and physiological markers. However, their influence on defensive responses to threat has yet to be investigated. This study examines whether a placebo manipulation can impact subjective pain ratings in response to the shock, as well as heart rate during shock anticipation, in healthy individuals. Participants (n=72) were tested in a Pavlovian threat conditioning paradigm over two days with a 24-hour interval, in a within-subject design. A sham analgesic electrical stimulation (TENS) was used to induce a placebo effect. The placebo conditioning process paired a placebo stimulus ("painful shock + TENS") with a low pain response, followed by two sessions of associative threat conditioning. Subjective pain ratings and heart rate, as an indicator of the freezing response, were measured across different conditions. The STAI-trait questionnaire was also completed. Results indicated higher subjective pain levels in response to the painful shock compared to the TENS shock during the threat acquisition phase. Importantly, during this phase, stronger heart rate deceleration, indicative of freezing, was observed when anticipating the painful shock versus the TENS shock. There was no evidence the placebo effect persisted during the threat retention stage, as there were no significant differences in heart rate while anticipating the two conditions. Trait anxiety did not significantly influence the placebo response. These findings demonstrate that a placebo intervention affects not only subjective experiences but also physiological responses to threat, highlighting the potential of using placebos as co-interventions for individuals experiencing anxiety.Show less
With an aging population, the need for informal care is rising, significantly impacting caregivers. The Oog Voor Naasten en Nabestaanden “Eye for Family Caregivers” (ON2) was a tailored...Show moreWith an aging population, the need for informal care is rising, significantly impacting caregivers. The Oog Voor Naasten en Nabestaanden “Eye for Family Caregivers” (ON2) was a tailored intervention aimed to involve volunteers and healthcare professionals in providing structural support to informal caregivers in palliative care settings in the Netherlands. The ON2 intervention was implemented with SMART goals, implementation intentions, a workshop, and training sessions with a duration of a year. The study employed a pre-post design to assess the care for informal caregivers by volunteers and healthcare professionals, with data collected via surveys from 98 healthcare professionals, 117 volunteers, and 229 informal caregivers across 15 healthcare organizations. Measures included inquiries about the ‘Wellbeing and Needs’ of informal caregivers, ‘Care Provided’ by volunteers and professionals and ‘Care Received’ by informal caregivers, perceived ‘Competence’ of volunteers and professionals to support informal caregivers, and informal caregiver ‘Satisfaction’. Post-intervention, professionals inquired about ‘Wellbeing and Needs’ from 76.41% and volunteers from 49.36% of informal caregivers. Healthcare professionals showed a significant increase in inquiries and perceived competence, while volunteers showed an increase in perceived competence alone. Informal caregivers reported higher ‘Satisfaction’ with the care they received post-intervention. The informal caregiver reported ‘Care Provided’, and ‘Care Received’ did not significantly increase post-intervention. The healthcare professionals' inquiries about ‘Wellbeing and Needs’ across different settings showed no significant overall change, but informal caregivers indicated more frequent inquiries in hospices and homecare compared to hospitals. Informal caregivers are an important resource for healthcare and their wellbeing is crucial to carry on their several roles. The ON2 intervention demonstrates that structural facilitation of informal caregiver support is achievable in palliative care settings.Show less
This study aims to investigate the effects of exercise-intensity on divergent creativity. It is hypothesized that exercise of moderate and high intensity enhance creativity more effectively than...Show moreThis study aims to investigate the effects of exercise-intensity on divergent creativity. It is hypothesized that exercise of moderate and high intensity enhance creativity more effectively than exercise of lower intensity. The study also investigates if arousal, positive high-arousal affect, and negative high-arousal affect serve as intermediary variables in this relationship. Scarce previous research has suggested a relationship between exercise-intensity and creativity, but studies comparing different exercise-intensities on creativity and potential underlying mechanisms were lacking. To address this knowledge gap, this study compares different intensities, namely low-intensity (cycling at 55% of maximum heart rate), moderate-intensity (cycling at 70% of maximum heart rate), high-intensity (cycling at 85% of maximum heart rate) and a control group, on divergent creativity (i.e., number and uniqueness of creative ideas); And looks at affect and arousal as underlying mechanisms. Happy (positive), elated (positive), upset (negative), tense (negative) and stressed (negative) are used as indicators for high-arousal affect and feelings of wakefulness and alertness as indicators for arousal. Participants in this study completed two appointments, of which the first appointment consisted of a fitness test to measure participants’ maximum heart rate. During the second appointment, participants were randomly assigned to one of the four conditions and their affect and arousal were measured before and after the exercise or control task. Creativity was measured after the exercise or control task was completed. A Kruskal-Wallis Test showed that participants in the moderate-intensity and high-intensity exercise did not show higher creativity. Further, macro PROCESS model 4 revealed a significant effect of moderate-intensity and high-intensity exercise on arousal in comparison to low-intensity exercise and a significant effect of moderate-intensity exercise on positive high-arousal affect, in comparison to the control group. Other than this, the model revealed that none of the mediators significantly explained a relationship between exercise-intensity and creativity. This study thus suggests that exercise-intensity does not play a significant role in creativity enhancement, nor does arousal or high-arousal affect. However, future research is needed to confirm this for other modes of exercise, regular exercise instead of acute bouts of exercise and for different individual characteristics, such as age and gender.Show less
Voorgaande onderzoeken tonen dat heteroseksuele mannen beter presteren op navigatietaken dan heteroseksuele vrouwen, homoseksuele vrouwen en homoseksuele mannen. Het huidige onderzoek bekijkt het...Show moreVoorgaande onderzoeken tonen dat heteroseksuele mannen beter presteren op navigatietaken dan heteroseksuele vrouwen, homoseksuele vrouwen en homoseksuele mannen. Het huidige onderzoek bekijkt het effect van seksuele oriëntatie, gender en geslacht op de prestatie op een navigatietaak. Het onderzoek verspreidde een online vragenlijst met navigatietaak onder 216 deelnemers met een gemiddelde leeftijd van 27 jaar oud. 65 van de deelnemers waren van het mannelijke geslacht en 151 van het vrouwelijke geslacht. Hiervan waren 151 deelnemers heteroseksueel en 65 niet-heteroseksueel. Uit de resultaten van het onderzoek bleek dat seksuele oriëntatie, gender en geslacht geen effect hebben op de prestatie van mensen op een navigatietaak. Dit kan komen door de kleine individuele groepen binnen de niet-heteroseksuelen, waardoor er geen goede conclusie over de aparte groepen getrokken kan worden. Toekomstige onderzoeken zouden meer LHBTQIA+ organisaties kunnen betrekken bij het werven van deelnemers.Show less
Transcranial magnetic stimulation (TMS) is a noninvasive neuromodulation technique showing promise in stroke rehabilitation, with evidence indicating significant enhancement in motor function of...Show moreTranscranial magnetic stimulation (TMS) is a noninvasive neuromodulation technique showing promise in stroke rehabilitation, with evidence indicating significant enhancement in motor function of the contralateral limb following treatment. While TMS appears promising for stroke rehabilitation, there is variability in the level of improvement individuals exhibit. This variability may be attributed to oscillatory neurophysiology, which refers to the rhythmic electrical activity of the brain. Therefore, this study investigated phase-dependent changes in cortical excitability after TMS among stroke patients in affected and unaffected hemispheres. We investigated motor-evoked and TMS-evoked potentials at four phases of the ongoing motor cortical mu rhythm (trough, peak, rising, falling) in both hemispheres (affected, unaffected). Participants comprised N=11 chronic subcortical stroke patients (6 female, mean ± std age: 58 y ± 11.4) with affected lateralized upper-limb impairment. Four blocks of 150 TMS pulses were applied on each hemisphere, targeting the primary motor hotspot of the first dorsal interosseus muscle of the contralateral hand. Participants watched nature videos during stimulation to maintain consistent attention levels. Cortical excitability was assessed by analyzing motor-evoked potentials (MEP) and TMS-evoked potentials (TEP). Results showed that motor responses (measured through MEP amplitudes) were significantly larger at the trough and rising phase compared to the peak phase. No significant differences were observed between the affected and unaffected hemispheres. TEP components, the brain signals in response to TMS, did not exhibit significant phase-dependent changes. While our findings showed a nonsignificant effect of stroke severity, exploratory correlation analyses presented a positive association between higher remaining movement function and enhanced phase-dependent responses to TMS. The findings build upon previous research indicating phase-dependent changes in cortical excitability for MEPs but not for TEPs. The larger MEP amplitudes during trough and rising phases suggest that TMS can be more effective at specific points of cortical activity. Further exploration is needed to assess the efficacy of phase-specific TMS interventions in clinical settings, potentially through larger-scale clinical trials with longitudinal designs and comparative effectiveness studies, aiming to evaluate functional outcomes and determine their impact on motor recovery.Show less
