Psychological flexibility is characterised as an individual's capacity to accurately adjust behaviour and cognitions in face of obstacles. It has been acknowledged to influence coping strategies as...Show morePsychological flexibility is characterised as an individual's capacity to accurately adjust behaviour and cognitions in face of obstacles. It has been acknowledged to influence coping strategies as well as increase quality of life. Because migrants and religious individuals have been shown to cope differently with life stressors compared to non-migrants and non-religious people, it is pertinent to examine whether this also applies for psychological flexibility. As a result, this study investigated which potential role psychological flexibility has the association of migrant status and religiosity with quality of life. This online study was conducted in the Netherlands in 2022. This offered a unique opportunity to examine the mentioned link, as this occurred during the COVID-19 pandemic. The design of the study was cross-sectional, and the number of participants accumulated to 1610 (M age: 37.8, 69.0% females). Out of which 323 (20.1%) identified as migrants and 415 (25.8%) affirmed to be religious. The screening instruments which measured psychological flexibility and quality of life were the FIT18 and the RAND-SF-36. In reference to the later the composite dimensions of physical health-related quality of life (PQOL) and mental health-related quality of life (MQOL) were used. Regression analyses examining the association of migrant status with PQOL and MQOL yielded insignificant results, with (p=.203) and (p=.577), respectively. In like manner, was no evidence found of an association of religiosity with PQOL (p=.573) and MQOL (p=.392). There was further no substantiation for a moderation effect of psychological flexibility on the association of migrant status and religiosity with quality of life. The interaction between migrant status and psychological flexibility were non-significant for PQOL (p=.160) and MQOL (p=.651). The interaction between religiosity and psychological flexibility was also non-significant for PQOL (p=.487) and MQOL (p=.530). Similarly, was no mediation effect found of psychological flexibility on the association of migrant status and religiosity with quality of life. Nevertheless, was greater psychological flexibility associated with better physical (β=.337, p<.001) and mental quality of life (β=.695, p<.001). In conclusion, this study emphasised the pivotal relation of psychological flexibility to both physical and mental quality of life during distressing circumstances.Show less