Research master thesis | Archaeology (research) (MA/MSc)
under embargo until 2024-10-19
2024-10-19T00:00:00Z
During the early modern period (1500-1800 CE), Europe was plagued by syphilis, a venereal infection caused by the bacteria Treponema pallidum, resulting in chronic and debilitating symptoms....Show moreDuring the early modern period (1500-1800 CE), Europe was plagued by syphilis, a venereal infection caused by the bacteria Treponema pallidum, resulting in chronic and debilitating symptoms. Desperate to resolve the infection, patients were often subjected to prolonged and extensive treatments with toxic mercury. Unfortunately, osteoarchaeological study of syphilis is challenging due to the limited skeletal visibility of the infection. Moreover, historical evidence is sparse and often influenced by sociocultural stigma attributed to the venereal nature of the disease. This scarcity of data on syphilis in the early modern period has limited more holistic research into the disease and its treatment. Therefore, this study adopted a multidisciplinary approach to investigate syphilis and its treatment at St. Gertrude’s infirmary (1382 - ca. 1611) in Kampen, the Netherlands, where presence of the disease has been previously reported. Human skeletal remains (n=79) were re-examined with a focus on treponemal disease, following the scoring system laid out by Harper et al. (2011). The potential therapeutical use of mercury was investigated by conducting archival research and multiple trace elemental analyses. Using portable X-Ray Fluorescence Spectrometry (pXRF) and Inductively Coupled Plasma-Mass Spectrometry (ICP-MS), subsamples of the skeletal assemblage were assessed on the presence of mercury in human bone. Scanning Electron Microscopy with Energy Dispersive X-Ray (SEM-EDX) was conducted to assess the potential uptake of mercury in dental calculus on the teeth. Osteoarchaeological study identified several diagnostic cases of treponemal infection at the site (n=5 or 6.33%), as well as a number of cases with lesions suggestive of treponemal disease. This finding demonstrates the influence of treponemal disease, likely attributable to venereal syphilis, at St. Gertrude’s infirmary in Kampen, especially when compared to the prevalence of the disease in human skeletal assemblages from similar Dutch sites. Research into historical archives indicated that mercury was indeed used therapeutically in Kampen during the 18th century. However, it showed no direct evidence for syphilis or mercury treatment at St. Gertrude’s infirmary in the period of interest (1382 – ca. 1611). Unfortunately, elemental analyses revealed no substantial evidence for significantly elevated mercury concentrations, although interesting trends were found. In particular, both pXRF and SEM-EDX analyses did not result in absolute and quantifiable mercury concentrations. While ICP-MS analysis showed absolute concentrations of mercury in a subsample of bone material, interpreting and contextualising these results remains challenging. These observations may be explained by a lack of available mercury treatment in Kampen or a preference for other treatment methods. Nonetheless, this study helps to understand syphilis and its treatment in the early modern Netherlands and provides an evaluation of chemical analyses to detect mercury in archaeological bone.Show less
The focus of this study is to assess sexual dimorphism of non-metric and metric characteristics of the mandible of a Dutch post Medieval rural population from the Middenbeemster polder in the...Show moreThe focus of this study is to assess sexual dimorphism of non-metric and metric characteristics of the mandible of a Dutch post Medieval rural population from the Middenbeemster polder in the province of Noord Holland in the Netherlands. The mandible is not seen as a reliable feature for sex estimation in research on Dutch Medieval populations based on non-metric traits. Studies on populations around the world show that the mandible is a reliable tool for estimating sex, provided that metric measurements of the mandible are used. This study focuses on the re-evaluation of the mandible as a reliable tool for sex estimation by studying both non-metric and metric sexual dimorphism of the mandible in a Dutch population. The development of a technique that reliably estimates mandibular sex in Dutch medieval populations would be a great contribution to the field of bioarchaeology. Sex estimation is paramount for the reconstruction of demographic structures of past societies. In this thesis sexual dimorphism based on both non-metric and metric is assessed. 90 samples from the Middenbeemster with known sex are used for measurement and observations. This sample consists of 40 females and 50 males. The non-metric scores are compared to known sex to assess reliability. The metric measurements are analysed using binary logistic regression and tree modelling to assess if the specific measurements are reliable in estimating sex of an unknown individual. The overall accuracy of the non-metric sex estimation is very low and therefore not reliable for further use. The metric measurements have a higher reliability rate, especially the bigonial breadth and the mean of the maximum ramus height. With the use of these two measurements a cross validated classification accuracy of 80.2 percent can be achieved. In conclusion, after re-evaluating the mandible it appears that the mandible can be used with high accuracy in sex estimation in the Dutch population of Middenbeemster and maybe in other North Western European populations from the post Medieval time period, which has to be assessed by future research.Show less