People with multiple sclerosis (PwMS) often experience symptoms that can have a significant impact on psychological and cognitive functioning. Research has previously shown a significant...Show morePeople with multiple sclerosis (PwMS) often experience symptoms that can have a significant impact on psychological and cognitive functioning. Research has previously shown a significant association between these two functions. The aim of this paper was to study the association between psychological factors (depression and fatigue) and cognitive functions (memory, verbal fluency, and information processing speed). Studying fatigue, depressed mood, and the combination between them can provide important indications to how psychological status relates to cognitive functioning. Cognitive functions of memory, verbal fluency, and information processing speed were measured through Buschke Selective Reminding test, Controlled Oral Word Association test, and the Symbol Digit Modalities test, respectively. Depressed mood was measured with the Hospital Anxiety and Depression Scale, and fatigue was measured with the Fatigue Scale for Motor and Cognitive Functions. Patients (N=124; mean age = 50.77 [SD = 13.5]; 25% male, 93% female; 9.7% PPMS, 28.5% SPMS, 61.3% RRMS) were categorized into four groups based on their depression and fatigue scores using clinical cut-offs (i.e., psychologically intact [no depressive mood, not fatigued], depressive mood but not fatigued, fatigued but no depressive mood, and psychologically impaired [depressive mood and fatigued]). Group did significantly differ on MS type (p < .05), Group 1 (psychologically intact) and Group 4 (no depressive mood but fatigued) were more likely to have a relapse-remitting disease course. However, findings suggest no significant association between group and cognitive functioning. Scores on the cognitive tests were similar across all groups (p = .203). This indicates that cognitive functioning is independent of psychological status. However, in light of the limitations, it is important to build on future studies to investigate this relationship further, to indicate a next step in the treatment and intervention of MS in terms of psychological problems, cognitive deficits, or both.Show less
Abstract The connection between hippocampus-dependent learning and the novelty of a previously experienced environment has been investigated through animal research for a longer time. In rodents,...Show moreAbstract The connection between hippocampus-dependent learning and the novelty of a previously experienced environment has been investigated through animal research for a longer time. In rodents, it was found that they showed theta band power while encoding memories, during the initiation of explorative movements. But there has been a scarcity of research looking at these connections in humans. This study aims to investigate the associations between memory types (landmark memory, as well as recall and recognition on an unrelated word learning task) and familiarity of the environment as well as theta bands in the brain. Thirteen men and women took part in this three-day EEG study. On the first day, participant first explored one environment during the exploration phase and later explored another time an environment that was either the same as before (familiar) or a new (novel) environment. On day two, they were then exposed to a new environment (novel condition), if they have seen two times the same environment on day 1, or to an environment that they have already seen on day 1(familiar condition) if they saw two different environments on day 1. On both days they had to complete a landmark memory, recall, and recognition task. On days two and three the participants did a delayed recall and recognition task. The EEG was used during all tasks on days one and two. The results showed that landmark memory was not affected by the novelty of the environment (p = .812). Word recall was also not affected by the novelty of the environment (p = .400), and neither was recognition (p = .227). There was more theta band power during the novel environment exploration than during the familiar environment measured (p < .001). Theta bands were not correlated with recall (p = .783) or landmark memory (p = .231). This study had a small sample, no cultural diversity, and a strict theta band inclusion criterion. Because of that, the results should be interpreted with caution and further studies should include a bigger sample, with different cultures, and perhaps a wider theta frequency spectrum. This study could help closing the gap between animal and human research, as well as create tools to assist people with learning difficulties.Show less
Childhood scarcity has long lasting effects that remain visible during adulthood. Much of the literature suggests that these effects are mostly negative, but some theories such as the Life History...Show moreChildhood scarcity has long lasting effects that remain visible during adulthood. Much of the literature suggests that these effects are mostly negative, but some theories such as the Life History Theory have inspired studies that show positive effects of childhood scarcity. The current work aims to highlight the effects of experiencing childhood scarcity on adult cognitive performance in a current financial scarcity situation. We hypothesized that people who experienced childhood scarcity performed better, on a memory and attention task during a situation of current financial scarcity, then people who had not experienced such scarcity. To test their memory we used a restaurant menu containing dishes with prices and calories that participants had to recall; further, to measure attentional shifting, the menu contained a discount code that participant could copy and paste in order to save money. In the experiment 190 participants were randomly assigned to two groups – respectively low budget and high budget condition. The hypotheses were not confirmed, however a significant effect of childhood scarcity on the memory of dishes’ prices and calories was found.Show less
