Psychotic experiences (PEs) occur in up to 30% of children, usually subsiding during adolescence. The presence of PEs alone can lead to mental distress; additionally its persistence can have grave...Show morePsychotic experiences (PEs) occur in up to 30% of children, usually subsiding during adolescence. The presence of PEs alone can lead to mental distress; additionally its persistence can have grave consequences for the child’s development. Neighborhood characteristics are a promising new frontier for research on the development of PEs in childhood and adolescence. The main aim of this study was to investigate the relationship between neighborhood social cohesion, living conditions, objective and perceived safety, and PEs at age 14. The secondary aim was to investigate the relationship of the aforementioned neighborhood factors with the trajectory of PEs from age 10 to 14. We ran a specificity analysis using depressive symptoms to evaluate whether the associations were indicative of a link with general psychopathology or specific psychotic spectrum outcomes. We used the Generation R cohort data on self-reported hallucinations and delusions, and the Wijkprofiel Rotterdam on social, safety, and physical characteristics of the neighborhood. In our multilevel logistic regression analysis, we found no evidence for an association of any neighborhood factors with PEs at age 14. There were trends demonstrating the potential association between living conditions and two outcomes: remission of PEs at age 14, and severe depressive symptoms. However, neither association survived multiple testing correction. We discuss the need for further research to ascertain whether the associations apply to general psychopathology or psychotic spectrum outcomes. Furthermore, we propose the need to clarify new potential associations of neighborhood factors with PEs.Show less