Background The number of students with an autism diagnosis is increasing at university. Previous research has shown that those students experience lower levels of social support. Previous research...Show moreBackground The number of students with an autism diagnosis is increasing at university. Previous research has shown that those students experience lower levels of social support. Previous research has also shown a positive link between social support and academic performance. However, there is limited research on this topic. Aim To explore the relationship between social support and academic performance in university students, and to check whether this relationship is mediated by stress, perceived self-competence, depression, or anxiety, and moderated by an autism diagnosis. Design and method Online survey. 222 university students (aged 18-56), 59 with an autism diagnosis (aged 18-39), and 163 without an autism diagnosis (aged 18-56), completed multiple questionnaires assessing participants’ academic performance, perception of their competence to do their class work, stress related to studying at university, anxiety, depression, and social support. Participants were recruited at Dutch universities. Results There was no relationship between social support and stress, perceived self-competence, depression or anxiety. There was no relationship between stress, perceived self-competence, depression or anxiety and academic performance. Autism diagnosis moderated the relationship between social support and depression, and the relationship between social support and anxiety. Limitations The results are reliant on self-reports. A snowball procedure was used for recruitment, which may have caused the sample to be unrepresentative. Conclusion Considering the differences in findings to previous research and the limited amount thereof, it remains unclear whether a relationship between social support and academic performance in students with autism is present, and whether the relationship is mediated by stress, perceived self-competence, depression or anxiety. Future research should examine gender differences, as well as a combination of different constructs.Show less