Neural gain is the mechanism underlying the stability/flexibility trade-off, which is fundamental for goal-directed yet adaptive behavior. Inspired by the development of a computational model that...Show moreNeural gain is the mechanism underlying the stability/flexibility trade-off, which is fundamental for goal-directed yet adaptive behavior. Inspired by the development of a computational model that estimates gain, we assessed whether people rationally modulate gain to demands for stability and flexibility. We designed two task-switch digit-classification experiments with 60 participants each, in which we manipulated the proportion incongruency (PI) in experiment one and cue-to-stimulus interval (CSI) in experiment two. Our results indicated that PI manipulation did not significantly affect gain, yet incongruency costs and switch costs demonstrated an increase in stability in response to high PI. CSI manipulation significantly affected both gain and incongruency costs, demonstrating increased flexibility in response to a short preparation time. Furthermore, we used questionnaires to assess participants' ASD and ADHD trait scores and tested whether these predicted biases in gain and/or impairments in gain modulation. Despite the lack of conclusive findings, this study offers insight in the relation between ASD and ADHD and neural gain. More studies that overcome our limitations may discover the impairments in neurocognitive mechanisms underlying psychological disorders and inform treatment. Altogether, our results indicate that people rationally adapt to demands for stability and flexibility following an antagonistic trade-off. Therefore, this study contributes to the research on neuromodulation and adds to the general understanding of attention. Our findings may also help to inform applied research on the benefits and drawbacks of stability and flexibility in the workplace. Thereby, managers could be made aware of the number of tasks assigned to their employees and whether the demand to switch between them is proportional to their difficulty.Show less
