Research master thesis | Developmental Psychopathology in Education and Child Studies (research) (MSc)
open access
2020-08-06T00:00:00Z
Children with autism spectrum disorder (ASD) are characterized by communication deficits. Emotions are part of interpersonal communication and adequate use of emotions are vital for successful...Show moreChildren with autism spectrum disorder (ASD) are characterized by communication deficits. Emotions are part of interpersonal communication and adequate use of emotions are vital for successful interaction. To see if children with ASD express emotions to the same extent, we compared 17 children with ASD (age range: 3-6 years) to 33 typically developing children of the same age on both on behavioral emotion expression and on psychophysiological arousal. The behavioral expression and psychophysiological parameters of emotion (heart rate and skin conductance level) were continuously measured during rest and a fear inducing paradigm. The groups did not differ on the intensity of negative or positive emotion expression. The ASD group had lower skin conductance levels during rest compared to the typically developing children and a more pronounced increase in psychophysiological arousal in response to a fear paradigm. To integrate these two separate measures of emotion, the concordance between the behavioral and psychophysiological components was evaluated. Negative emotions were related to heart rate in the ASD group and to skin conductance in the control group, but the strength of the correlation did not differ significantly between the two groups. Considering the health and behavioral risks associated with abnormal levels of emotional arousal, the specific effects of deviant emotional arousal in children with ASD need to be further explored. Targeting psychophysiological levels of arousal in interventions might be an effective approach to ameliorate challenging behavior in children with ASD.Show less
Research master thesis | Developmental Psychopathology in Education and Child Studies (research) (MSc)
open access
2017-08-28T00:00:00Z
This study was conducted to assess subjective quality of life and to distinguish predictors of quality of life in young adults with autism spectrum disorder (ASD). Young adults with ASD enrolled in...Show moreThis study was conducted to assess subjective quality of life and to distinguish predictors of quality of life in young adults with autism spectrum disorder (ASD). Young adults with ASD enrolled in higher education were compared to control students without ASD with respect to quality of life, executive functioning, motivation performance, social anxiety, emotion regulation, stress coping abilities, ASD symptoms, adaptive functioning, and self-reflection. Young adults with ASD reported lower subjective quality of life than control peers and showed higher impairment in all of the above-mentioned areas. Within the ASD group, low initiative taking, high internalizing problems, and high negative tension in social situations predict lower quality of life. Together, these findings indicate that deficits in the stress regulation system lead to lower subjective quality of life in young adults with ASD, despite their high functioning.Show less
Research master thesis | Developmental Psychopathology in Education and Child Studies (research) (MSc)
open access
2017-09-20T00:00:00Z
One of the dysfunctions associated with Klinefelter syndrome (KS) (47,XXY) are difficulties in social functioning, which may arise as a consequence of executive functioning (EF) and Theory of Mind ...Show moreOne of the dysfunctions associated with Klinefelter syndrome (KS) (47,XXY) are difficulties in social functioning, which may arise as a consequence of executive functioning (EF) and Theory of Mind (ToM) deficits. In this study, the influence of EF on ToM skills in KS boys was examined, as well as how these skills relate to autistic features. ASD traits were assessed with the parent-report Autism-Spectrum Quotient. ToM skills were measured with the Social Cognitive Skills Test. EF skills were measured with the Clinical Evaluation of Language Fundamentals and Amsterdam Neuropsychological Tasks. 28 KS boys (Mage=13.2, SD=3.0) participated in this study, along with 45 ASD boys (Mage=11.9, SD=2.0) and 46 boys from the general population (Mage=12.2, SD=2.9) as control groups. KS boys showed substantially elevated levels of ASD traits compared to the general population, but lower levels than ASD boys. In addition, difficulties regarding ToM and cognitive flexibility were more prominent in KS boys than in ASD boys compared to the general population. ToM task performance could partly be explained by spatial WM and attention switching (as autistic trait) could partly be explained by ToM skills in KS boys. The current study highlights the importance of attention modulation skills and ToM skills in social functioning of individuals with KS, providing promising insights regarding prevention and intervention. Future studies should focus on the effectiveness of enhancing EF skills in KS boys and the role of the X chromosome in vulnerability for autistic traits.Show less
Research master thesis | Developmental Psychopathology in Education and Child Studies (research) (MSc)
open access
2014-08-16T00:00:00Z
The aim of this study was to expand the knowledge about the specific social-emotional difficulties within Klinefelter syndrome (47, XXY) by measuring attention to social cues, emotion recognition...Show moreThe aim of this study was to expand the knowledge about the specific social-emotional difficulties within Klinefelter syndrome (47, XXY) by measuring attention to social cues, emotion recognition skills, empathy and emotional arousal. 14 participants with Klinefelter syndrome (age range 16-56) and 14 control participants (age range 22-60) were included. All participants watched four video clips designed to evoke empathy, and filled out a questionnaire about their own and the main character’s emotions after each video. Furthermore, they completed an emotion recognition task consisting of 80 pictures of faces with a neutral, happy, scared or angry expression. During both tasks eye movements and fixations were measured. Electrocardiogram and skin conductance measurements were done at baseline, during the video clips and during the emotion recognition task. Participants with Klinefelter syndrome had equal emotion recognition scores compared to the control group, but empathy scores were lower for the Klinefelter group. Participants with Klinefelter spent less time fixating on eyes and more time fixating outside the face during the emotion recognition task. No group differences in overall fixation times were found during the videos, but longer fixations on eyes and mouths and shorter on objects predicted better empathy scores. Psychophysiological responses differed between groups during the empathy videos: participants with Klinefelter showed somewhat stronger skin conductance reactions than controls. The current results can contribute to the development of interventions for Klinefelter syndrome. Moreover, the results can give insight into the role of the X-chromosome in the relation between (social) attention processes and social-cognitive functioning.Show less
Research master thesis | Developmental Psychopathology in Education and Child Studies (research) (MSc)
open access
2017-07-19T00:00:00Z
The investigation of aggressive behaviors in specific types – reactive and proactive – on the basis of knowledge about executive dysfunctioning is important for determining both the etiology and...Show moreThe investigation of aggressive behaviors in specific types – reactive and proactive – on the basis of knowledge about executive dysfunctioning is important for determining both the etiology and the treatment strategies for aggression. The present study aimed to identify executive functions as the mechanisms underlying reactive and proactive aggression. Twenty-seven boys from 7 to 12 years old (M = 9.78, SD = 1.37) participated in this study. We created a sample including boys with different types of aggression and a wide range of aggression scores. Several (computerized) neurocognitive tasks were used for the measurement of the executive functions: inhibition, attention, frustration tolerance, cognitive flexibility and planning. A teacher questionnaire was administered for the reactive and proactive aggression scores of the boys. We found that the executive dysfunctions were associated with higher levels of aggression. Inhibition problems were associated with both types of aggression, but we also delineated unique factors in the prediction of reactive or proactive aggression. These results are not only important for theoretical frameworks about the etiology of aggression, but we can also underpin the importance of stimulating the development of specific executive functions for the prevention and treatment of different types of aggression.Show less
Research master thesis | Developmental Psychopathology in Education and Child Studies (research) (MSc)
open access
2017-01-01T00:00:00Z
The aim of this study is to explore the role of language skills, communication and emotion regulation in relation to the degree of externalizing behavior. Studying children with an additional X...Show moreThe aim of this study is to explore the role of language skills, communication and emotion regulation in relation to the degree of externalizing behavior. Studying children with an additional X chromosome, who are known to have language deficits, can reveal insights into the underlying mechanisms of the development of externalizing behavior problems. A total of 85 normal developing children (34 boys and 51 girls) and 33 children with an additional X chromosome (16 girls and 17 boys) participated in the study. All children were tested on language skills (vocabulary, word associations, formulating sentences and concealed meaning) and emotion regulation (Cognitive Emotion Regulation Questionnaire- kids). Parents completed questionnaires to assess social communication (Autism Questionnaire-children and Pragmatics Profile) and externalizing behavior (Social Skills Rating System and Child Behavioral Checklist).Our results indicate poorer language and social communication skills, more externalizing problem behavior and lowered levels of self-control in children with an additional X chromosome. Emotion regulation strategies were similar to controls although rumination was more often used as a regulation strategy. Though no direct association between language skills and externalizing behavior was found, findings did indicate an indirect association via social communicational skills. The findings also suggest that emotion regulation was linked to externalizing behavior. Future studies should focus on these possible risk factors in relation to the development of externalizing behavior. This might provide more insight into the treatment of the children with an additional X chromosome, as they have an high risk to develop externalizing behavior problems, early in life.Show less
Research master thesis | Developmental Psychopathology in Education and Child Studies (research) (MSc)
open access
2017-01-01T00:00:00Z
Individuals with a SCT characterized with an additional X chromosome encounter difficulties in social functioning, which is most prominent in there higher susceptibility for developing autism. The...Show moreIndividuals with a SCT characterized with an additional X chromosome encounter difficulties in social functioning, which is most prominent in there higher susceptibility for developing autism. The current study aimed to systematically address underlying mechanisms related to these difficulties by examining differences in executive functions of children with a SCT karyotype and typically developing children. Furthermore, we examined to what extent executive function deficits were related to higher autism traits. 135 boys and girls (M = 11.4, SD = .2) participated in this study, 85 typically developing children and 50 children with a SCT. We used computerized tasks, a questionnaire, and a verbal task to asses a wide range of executive functions. A questionnaire was used to address autism traits. Children with a SCT showed increased difficulties in encoding verbal information, cognitive flexibility, sustained attention, and more difficulties in executive functions during daily life compared to the typically developing children. Higher autism traits were associated with more difficulties in executive functions during daily life, cognitive flexibility, and encoding verbal information. This provides evidence for impairments in executive functions among individuals with a SCT of which some of them are related to increased difficulties in social functioning. Limitations and implications for future research are discussed.Show less
Research master thesis | Developmental Psychopathology in Education and Child Studies (research) (MSc)
open access
2016-09-22T00:00:00Z
The main objective of this study was to unravel characteristics of Autism Spectrum Disorder (ASD) by studying autism traits, social cognition, and gender differences in Klinefelter Syndrome (KS)...Show moreThe main objective of this study was to unravel characteristics of Autism Spectrum Disorder (ASD) by studying autism traits, social cognition, and gender differences in Klinefelter Syndrome (KS) and Triple X syndrome. ASD traits were assessed with the parent-report Autism Spectrum Quotient. Social cognition was measured with the Social Cognitive Skills Test. Participants included 17 KS boys and 16 Triple X girls (Mage = 12.0 years, SD = 2.6), and 85 control children (Mage = 10.6 years, SD = 1.1). Our results showed that both boys and girls with an extra X chromosome show substantially elevated rates of ASD traits compared to controls. In addition, our study is the first to show that KS boys and Triple X girls have overall impaired social cognitive skills and function at a lower social cognitive level than typically developing children. Our study provides guidelines for the design and enhancement of screening instruments and treatment programs, which will benefit the development of these children. Future studies should focus on identifying risk factors endangering the development of children with ASD and those that are born with an extra X chromosome.Show less
Research master thesis | Developmental Psychopathology in Education and Child Studies (research) (MSc)
open access
2016-09-22T00:00:00Z
This study seeks to uncover the externalizing behavioral phenotype of extra X chromosome children, and discover the role of emotion-regulation and executive functioning (EF) deficits in its...Show moreThis study seeks to uncover the externalizing behavioral phenotype of extra X chromosome children, and discover the role of emotion-regulation and executive functioning (EF) deficits in its development. Participants included extra X chromosome children (N = 29, 16 girls and 13 boys) and control children (N = 84, 33 boys, 51 girls). Ages ranged between 7 and 16 (Mage = 10;3, SD = 1;7). Externalizing behavior was assessed with the Child Behavior Checklist, the Cognitive Emotion Regulation Questionnaire assessed emotion regulation and two tasks of the Amsterdam Neuropsychological Tasks battery measured EF. To provide a detailed picture of overall social functioning of the participants the Social Skills Rating System was used. Results showed that extra X chromosome children show more externalizing behavior, more mental flexibility deficits and nearly significantly more rumination. In extra X chromosome children, externalizing behavior was positively related to inhibition deficits and to rumination levels. Emotion regulation and EF were not related but children exhibiting less rumination were more dependent on their EF in the prediction of externalizing behavior. Implications include evidence for the role of neuropsychological deficits in externalizing behavior and possible guidelines for the treatment of children with an extra X chromosome and externalizing behavior.Show less
