Describing the motion of natural fragments in human tissue is crucial for lethality and vulnerability studies. The motion of small compact fragments is simulated by small cubes, cylinders and FSPs....Show moreDescribing the motion of natural fragments in human tissue is crucial for lethality and vulnerability studies. The motion of small compact fragments is simulated by small cubes, cylinders and FSPs. Two models that describe the penetration of these small compact fragment are ICARUS and WTI. However, bigger elongated fragments are also released during explosions. Describing the motion of elongated natural fragments is done by implementing the angle dependency in the presented area. This angle is found by solving the conservation of momentum. The developed model “Velocity Retardation of Elongated Cylinders” (VREC) solves the conservation of momentum and uses the angle to calculate the velocity retardation. The model is validated by comparing the expected velocity retardation with experimental data obtained from shooting tumbling cylinders at gelatin. The velocity retardation from the experimental data was similar to the velocity retardation calculated by VREC, while the velocity retardation calculated by ICARUS did not accurately describe the velocity retardation of the elongated cylinders at low or high impact angles. ICARUS did describe the penetration of cylinders with impact angles between 30o and 60o accurately. For small compact fragments, both models, VREC and ICARUS, describe the penetration accurately.Show less
Α-synuclein is a small 14 kDa protein, which is believed to play a role in the Parkinson’s disease. The aggregation process of α-synuclein could be the reason for the death of the neural cells in...Show moreΑ-synuclein is a small 14 kDa protein, which is believed to play a role in the Parkinson’s disease. The aggregation process of α-synuclein could be the reason for the death of the neural cells in the human brain during the disease. In order to understand this aggregation process, we need to set up a method for measuring the small aggregates of α-synuclein. This report will show the results of burst analysis, Fluorescence Correlation Spectroscopy in solution and in gel. Using the last method, we can find a size dependence on the diffusion coefficient of -1.64. FCS in gel could be performed for finding the early events in α-synuclein aggregation (monomer, dimer and tetramer)Show less
